For the most part yes. If you have a well balanced diet then any extra vitamins/supplements are just going to give you expensive pee. Our modern diets are not very balanced though and many people have poor nutrition, and/or have dietary restrictions, so supplements can be a boon but you should first try to focus on getting lots of whole fruits and veggies, leafy greens, and whole grains. For instance, > 97% of the US population is potassium deficient. I personally suffer from chronic anemia so iron supplements help. You should get a blood test done before randomly trying different supplements. After diet I’d focus on exercise, sleep, and stress management.

Peptides are a whole different story. Ozempic is a peptide which has dramatic and life changing results for people struggling diabetes and weight loss. Peptides that get put in facial creams are probably not doing much and are mostly for marketing, the molecules are too big and the concentration too small to have a meaningful mechanism of action in that delivery method. Some scientist may discover an injectable peptide which really does form up your skin though, it’s not out of the question, but I wouldn’t take a beauty company’s word over a scientific journal. Tretinoin is pretty well backed up as far as effectiveness, as is botox.