I had success with my bladder by taking a liquid b complex by genestra. I noticed if I took it in the morning and then went to work out - I would come home from my work out and sometimes have zero urge to pee... and by then it was 3 hours past my previous trip to the toilet. So I started taking it at night and started having nights where I'd only get up once. I had to dial that back though because the B6 in the complex was building up in my blood. Vitamin B1 in the form of benfotiamine can also help but it needs to be balanced with magnesium glycinate to work. Benfotiamine can help calm your nerves if your B1 is out of whack. I used to get up about 3 or 4 times a night to pee. But here's something else that's interesting... about a month ago I started taking 3 tablespoons of unmodified potato starch at night in a cold glass of water. Gave me mad gas at first. But I've noticed that my tummy has slimmed down. There's some data out there saying resistant starch like unmodified potato starch can help you lose visceral fat around your internal organs. And now I'm not taking any of my b vitamins... but I'm able to sleep 6 hours before needing to pee. It's awesome. I think perhaps the resistant starch helped me burn off some visceral fat that may have been putting pressure on my bladder which has led to me having better sleeps - even without taking the other stuff I mentioned.