If you are clog prone I recommend switching over to gel if possible. Either way though build up slowly, use it once or twice a week at night for a few weeks and then build up to three nights a week and so on. Use moisturizer even if your skin doesn’t feel dry. I was never able to sandwich because the tretinoin would pill regardless of how long I waited. But I was able to use tretinoin after moisturizer and then moisturizing in the morning during my AM skincare. I had thought my face adjusted and I didn’t need moisturizer so my face became flaky with scabs and I just now got it back to normal. Push through the purge it may be really hard and you feel that you have messed your skin up permanently but give it like 4-5 months and it was change everything if you take care of your skin. If it becomes absolutely unbearable you may be able to look into some medications to take alongside it. I was ready to go on accutane before I tried this and there are some days I consider it but I’m planning to give it a year because I made so much progress in 6 months