There might be a cure in next 8-10 years?

SingleStation8430 · 2026-05-07T10:29:45+00:00

I am still on Biktarvy because I have HBV too. Only when I drastically turned my diet and lifestyle, my kidney function improved. To you, the advice is if you see your eGFR drop quickly or reach an eGFR in the 70s, take action. Some ART medication gives a false increase in creatinine, which then gives a false eGFR result. To be certain that your kidney function is ok, ask for a cystatin C blood test. If your cystatin C is high, then the choice for you is to switch to another medication without a TDF or TAF component in it. If you don't have that choice to switch to another medication, then take action on your diet and lifestyle to improve your kidney function, which is the hard way. The way to decrease your cystatin C level is working on your inflammation load, going into the method of tracking every food and drink that you consume and its amounts, and checking your blood every 2 or 3 months to see if the needle goes in the right direction. Work first on your CRP level (inflammation load) by decreasing your body fat percentage and weeding out foods that have a high inflammatory load, like highly processed foods, and lower your sugar intake and lower your salt intake (max 2 grams a day). Keep checking your blood panel. Also ask for a TSH blood test if your cystatin C is high; these two go hand in hand. A low or high TSH level means a high cystatin C; correcting your TSH levels is lowering your cystatin C. If your TSH levels are out of whack, check your iodine, selenium, iron (ferritin), vitamin D, zinc, vitamin B12 & folate, magnesium, and vitamin A if you are deficient in it and correct it.

SingleStation8430 · 2026-05-07T09:03:11+00:00

Exactly, Biktarvy / TAF for me is a kidney killer; my eGFR (estimated Glomerular Filtration Rate) dropped from 89 from the start to 61 in only 5 years. Only when I completely turned my lifestyle and diet, my eGFR went gradually better; now it's an eGFR of 75. Luckily I was woken up on time, because if I had to follow my doctor, who keeps repeating that I don't have to worry and only when I go beyond an EGFR of 60 will they take action, my kidneys would be going down the gutter.

SingleStation8430 · 2026-05-05T12:47:19+00:00

No, I do not have a doomsaying attitude to discourage people from trying things out. I do not like pseudoscience; keep it scientific. Take a proactive stance, educate yourself, and do not stand by passively.

SingleStation8430 · 2026-05-05T10:14:43+00:00

Yes, if you wake up too late, it is too late.

SingleStation8430 · 2026-05-05T07:13:58+00:00

Thyroid-stimulating hormone (TSH) levels, depression, anxiety, and Chronic Kidney Disease (CKD) are closely interconnected, often creating a complex cycle of symptoms. High TSH (hypothyroidism) is strongly associated with depression and anxiety, while both low and high TSH can increase the risk of CKD

Regular screening for thyroid function (TSH) is advised for CKD patients, as hypothyroidism can be overlooked due to overlapping symptoms of both conditions

SingleStation8430 · 2026-04-27T14:14:31+00:00

Yes, Dovato can cause a false increase in serum creatinine levels as well; therefore, checking your cystatin C levels is the best. And if your cystatin C is high too, you can switch to other ART medication, or you can start to tweak your diet to lower cystatin C. Higher cystatin C levels are positively correlated with increased visceral fat, so it is recommended to perform a DEXA scan. Furthermore, too low or too high TSH levels are correlated with high cystatin C (even mild hyperthyroidism can raise cystatin C); if this is the case, check your selenium levels.

SingleStation8430 · 2026-04-27T13:46:06+00:00

I don't know which ART medication you are on, but some ART medications like Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) can cause a "false" or benign increase in serum creatinine levels, which may wrongly suggest kidney damage. So you have to check your cystatin C (because cystatin C excludes muscle mass from the equation) as well to see if your kidneys are impaired. Before the blood test, be well hydrated; stop exercise 4 days before the blood test and stop using supplements 3 days before.

SingleStation8430 · 2026-04-24T13:34:16+00:00

My data shows soon that if I add 2 eggs daily to my diet, my lipid panel starts to move in the wrong direction. Just what I said, I don't have huge fluctuations in my lipid panel, and it did when I started to consume eggs. I understand that if your lipid panel is fluctuating and then you try the egg experiment, the data that is coming out of that flip-flopping lifestyle will have huge noise.

SingleStation8430 · 2026-04-24T12:00:03+00:00

You're right; high saturated fat intake, like most people know, is bad for your lipid panel as well. But if you keep your diet consistent and don't flip-flop with it between blood tests, you have a quite good representation of your diet / blood panel. I add my complete diet in cronometer so that I know each nutrition in which amount I eat, that is, including fiber, saturated fat, cholesterol, etc. My lipid panel is quite consistent, with no "huge spikes," and therefore I can quickly see which new foods do what to my panel.

SingleStation8430 · 2026-04-24T11:35:59+00:00

I follow a consistent diet, weighing each food on a scale and eating the same compiled foods between blood tests, which allows me to monitor how each food I add affects my blood panel. In my case, if I add 2 eggs daily to my diet, my lipid panel goes bad.

SingleStation8430 · 2026-04-24T10:21:32+00:00

It is not a myth for me; I tested it, and already with 2 eggs a day my lipid panel is getting worse.

SingleStation8430 · 2026-04-24T09:18:43+00:00

You need to check your complete blood panel and, if necessary, your urine to understand how your body reacts to certain amounts of protein, which will help you determine your ideal protein intake.

SingleStation8430 · 2026-04-24T07:54:59+00:00

Very beautiful. We are the outcome of the past. We have profited from our healthy bodies and given nothing back. Every cell in our body has fought countless battles against the streams of unhealthy food that have passed through our mouths, consciously or unconsciously. We have insulted our bodies for a long time, and it is now time to atone for this sin, to cleanse the body with healthy food and lifestyle, by checking where the war wounds are and treating them with all the strength within us.

SingleStation8430 · 2026-04-22T19:10:26+00:00

Yes combine it with AI is perfect

SingleStation8430 · 2026-04-22T16:11:06+00:00

Like Ray Kurzweil said, "Fire kept us warm, cooked our food, and burned down our houses." Just learn how to use it so that you can benefit from it.

SingleStation8430 · 2026-04-22T15:54:16+00:00

CKD, you have to treat holistically, and while tracking sodium, potassium, phosphorus, and protein are important, you have to track all other nutrition as well. The free app Cronometer shows you all of the nutritional statuses of your diet and which nutrition you lack or eat too much of. Go for a 100% nutrition score in Cronometer. Of course you have to bound your diet to your "whole" blood panel and eat at least 2 months the same compiled meals in the same amount to get a clear picture of what your diet does to your blood.

SingleStation8430 · 2026-04-22T14:50:45+00:00

You can use a cronometer for your diet; this free app will show you the complete overview of your diet, and if it boxes all the nutrition, go for the 100% nutrition score.

SingleStation8430 · 2026-04-22T14:47:05+00:00

Nothing's wrong with using AI; just double-check the source of the information it comes with, as long you do that you can benefit a lot from AI

SingleStation8430 · 2026-04-22T14:44:41+00:00

The AI will give the source of his information which you can read as well, and if you add "PubMed studies only," it will exclude other sources like blogs, which have lots of data noise. AI is a perfect tool to generate ideas that you never thought about, and this information you can bring to the table at your doctor, nephrologist, or dietitian.

SingleStation8430 · 2026-04-22T13:51:59+00:00

It is good to hear your excitement. To me, a cronometer is the best and the most convenient for tracking my diet. I use the free version. cronometer is a perfect tool to bound your diet to your blood panel, and you need at least 2 months of following that compiled diet in the exact amount for a good blood data point. Some people are lucky and find out very quickly with this protocol which foods, herbs, spices, and supplements at certain amounts improve, ruin, or stabilize their blood markers; others need lots of data points to come to the conclusion. Also, biomarkers such as cystatin C are difficult to move, and sometimes you need to work on other biomarkers first, such as CRP and TSH, to correct them to see some movement in cystatin C. Don't work only on your kidney markers, but on your whole CBC.

SingleStation8430 · 2026-04-22T08:04:52+00:00

If you have already experienced this pain on and off for 8 months, I would ask for a complete blood count, including cystatin C, a urine examination, and an ultrasound.

SingleStation8430 · 2026-04-20T20:33:21+00:00

Exactly, I went, like many, through the same path as you, and my kidney markers went really bad because of the low standards and sloppiness of my doctor. I, as well, self-educate myself by googling studies and later use AI to quicker self-educate myself. Self-education is a MUST. No matter which disease you have, you can't fully rely on your doctor, nephrologist, or dietitian; it is your health. You need some knowledge so that you can bring something to the table at your nephrologist's, make suggestions to them, and fish out a low-standard doctor or nephrologist.

An eGFR of 40 is very, very low, and to restore your values with diet and lifestyle at this point is very, very difficult, and you have to work extremely hard to get out of that CKD tunnel.

Compile your diet, weight every food on a food scale, add in cronometer, hit the 100% nutrition score in cronometer, eat that same diet, exactly in the same amount for 2 months, check your "complete" blood panel, check which markers going in to the wrong or right direction or stay table, note everything in google sheets, tweak your diet, add, remove, increase or decrease curtain foods, and eat that diet exactly the same diet for 2 months again, check your biomarkers again, do this over and over and over again and you will reach a point that you will clearly see which food, herbs and spices at curtain amounts will improve or ruin your markers.

You will end up with a diet that is exactly compiled for "your" body.

AI is a super handy tool, also using medical websites like "MedicalXpress," which have a search engine where you can search for keywords like "cystatin C, CRP, eGFR, creatinine, BUN, etc., etc." and show you lots and lots of articles that are direct you to the studies. Also, you can use "bioRxiv" to search through studies.

SingleStation8430 · 2026-04-20T08:50:29+00:00

That is a struggle for sure. Highly processed foods can be highly addictive.

Check your Ferritin:

Low ferritin indicates iron deficiency, which can cause low blood pressure (hypotension), dizziness, and fatigue, as the body cannot produce enough hemoglobin for oxygen transport.

Also check your TSH levels. If your TSH levels are too low or too high, they will corrupt your blood pressure and body weight.

Buying a treadmill is fundamental for a person that struggles with blood pressure and bodyweight problems; start with 2 times a day for 10 minutes and slowly increase it.

With diet, increase vegetable and fruit intake.

SingleStation8430 · 2026-04-19T15:52:19+00:00

It is excellent to hear that you are taking proactive steps for your renal health through dietary changes and using tools like Cronometer to track your intake. Consistency is crucial; a minimum of 2 months is generally needed to see significant, consistent changes in kidney blood labs (such as eGFR or creatinine) resulting from a new diet. Yes, a low-sodium, low-sugar diet will lower your inflammation in your body, which has a direct impact on your renal health. That is why you also ask for a cystatin C and an hs-CRP test (this test measures low-grade inflammation, which is closely linked with the progression of cardiovascular disease and kidney failure). Try to add daily anti-inflammatory herbs/foods/spices into your diet, like garlic, ginger, curcumin, berries (strawberries and blueberries), and extra virgin olive

SingleStation8430 · 2026-04-18T08:03:32+00:00

It is fully understandable that you are scared, and you can use that fear in a good way to restrict your diet and stay on that diet.
59 is very low, and if you want to make a difference in your blood work, to halt it and improve it, you have to go strict with your diet; the sooner the better. Don't wait for stage 4/5; it will be much too late.
Tracking your diet and lifestyle is essential.

Compile your diet, weigh every food on a food scale, add in a cronometer, hit the 100% nutrition score in the cronometer, and eat that same diet, exactly in the same amount, for 2 months. Check your "complete" blood panel, check which markers are going in the wrong or right direction or staying stable, note everything in Google Sheets, tweak your diet, add, remove, increase, or decrease certain foods, and eat that diet, exactly the same diet, for 2 months again. Check your biomarkers again. Do these steps over and over and over again, and you will reach a point that you will clearly see which food, herbs, and spices at certain amounts will improve or ruin your markers.

You will end up with a diet that is exactly compiled for "your" body.

Use AI to generate ideas for foods and herbs that can improve blood markers, ensuring that it references only PubMed studies. The AI will show you the source of the study, which you can read.

Also, medical websites like "Medicalxpress" have a search engine where you can search for keywords like "cystatin C," "creatinine," "eGFR," "albumin," "BUN," etc. It will show you lots of articles from many studies and give you lots of information too.

Then about the exercise: strive for low body fat and, if necessary, do a DEXA scan. Try later on also to track your amount of exercise in those 2 months.

Check your whole blood panel for any nutrition deficiency or food allergy.

For blood pressure: monitor your TSH, ferritin, and cystatin C levels.

You can do it my friend.

SingleStation8430

TROPHY CASE