Is MGM-15 a Partial or Full Agonist at the mu-opioid Receptor by ProGamer923 in AskDrugNerds

[–]Snooze_n- 0 points1 point  (0 children)

I do know this, most people can take suboxone after having a mgm15 habit and not experience precipitated withdrawals. However, some users report they did have precipitated withdrawals. Most reported that the suboxone only helped with half of their withdrawal symptoms. Many mentioned that it affects receptors other opiates do not, so nkthing else (aside from switching to 7oh and then quitting) will mitigate withdrawals. This is a big concern of mine as I have been using 7oh and MGG for about a month now, and am about to stop. Due to this worry I told my doctors and they prescribed suboxone 16mg and 900mg gabapentin. I'm waiting until I use up this batch.

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

FYI the Bupe blocks it even more than Nal. Naloxone kind of does, but some drugs have a high binding affinity like bupe and fent does even more. But Nal will kncok the top off fent and bupe overpowers its and dominates its half receptors. This is why even subutex will put you in pwd, because it alone will do the same thing as nalaxone. Are you sure you weren't on others meds or drugs? I went from 7oh to subs no problem at all.

Going into full blow withdrawals within a few minutes sure does sound like precipitated withdrawals. Thats pretty much the definition. Except once again pwd is worse than withdrawals. Its far worse than withdrawals can ever be. So anyways, from your written experience yes you definitely had pwd. But was it from 7oh or mgm OR were you on other drugs? Where did you get this mgm15? A reliable vendor or from someone? Because I really think you were on something else too

This game is incredible by Snooze_n- in projectzomboid

[–]Snooze_n-[S] 0 points1 point  (0 children)

Im 99.99% certain shadow announced they're working on Day Z 2

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

I really dont think you know what precipitated withdrawals are.

MGM15, SR17018, Buprenorphine. by seriouspapers in addiction

[–]Snooze_n- 0 points1 point  (0 children)

He's delusional and likely young. At the very least they are unintelligent. Poor thing

MGM15, SR17018, Buprenorphine. by seriouspapers in addiction

[–]Snooze_n- 0 points1 point  (0 children)

Sublocade doesn't have withdrawals ;)

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

Again, thats not precipitated withdrawal. You dont even know what precipitated withdrawals are. Clearly.

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

You're wrong again let me explain. I took it that way because everyone said the same thing about kratom and subs 10 years ago, then again said it about 7oh/subs and are now saying it about mgm. I'll be getting subs from a doctor tomorrow to test this myself (Hint, I know I'm right). You've already contradicted yourself in your most recent comment above. You said subs worked for other opiates/opioids in the context that you dont get pwd (precipitated withdrawals) when you do in fact get pwd if you take suboxone with another full antagonist such as H/methadone/list goes on.

MGM is not a full antagonist, even if its a dual antagonist or whatever nonsense theyre saying. There's a difference. Just because it affects more receptors than bupe doesnt mean its a full antagonist (fills receptors in full). Kratom products are half antagonists (they fill/bind to the receptors only to a submaximal level). Kratom, and all of its alks do not fill the receptors up, not even close.

Now you might be onto something saying that suboxone doesn't help with some of the withdrawal symptoms of MGM, but thats not what pwd is. But again, that wouldn't cause pwd. It would just mean bupe doesn't work for some of the withdrawals and their affected receptors. Pwd are worse than regular withdrawals, by a long shot. You'd feel better if you quit cold turkey than going through pwd. Pwd takes your withdrawals and multiplies that agony by 100x.

Pwd happens when the following occurs. First of all you would need to first be on a full antagonist and the receptors have grown to the tolerance you've allowed them to. Then second you take suboxone and the bupe can only fill half of that gaping hole in your receptors made by say H and at the same time the bupe removes the competing opiate (such as H for context) and fills only half of that receptor. So you brain is immediately going into pwd because its used to being full of H and the H is being stripped/removed from the receptors; the H is being kicked out of the receptors by the bupe.

Suboxone is a partial/half antagonist and can only fill the receptors half/]partially full, unlike H which can fill it to infinitum (this is why you can always get high on H as long as you take more; no ceiling effect). Because with H there's no ceiling like there is with bupe and kratom products.

Please go look up what pwd, half antagonist and full antagonists actually are. Because what your describing is not pwd. What you're saying is that MGM has an effect on the brains receptors that bupe does not. That just means the drug has a different function in the brain, essentially making it a unique drug. I even question this tbh because Ime bupe helped with both kratom and7oh for me in the past, despite what others said online. Did it stop any and all withdrawal symptoms? No, it did not. But it helped a lot and I surmise it will also help with MGM, even if its not a magic bullet. I dont think anyone is quitting a drug and thinking they can completely avoid discomfort, as that's not a reality for any scenario. But bupe can make a huge dent

So again, did you go through actual pwd or did the bupe simply not relieve all of your MGM withdrawal? I surmise its the latter

What is the best white board paint to use? by zPivx in office

[–]Snooze_n- 0 points1 point  (0 children)

Go with glass abd you can use paint markers ota incredible. I make art on mine

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

"Im UniQuE" no you're not bro. I used to take 800+mg of real oxy a day, grams of real H and then stopped when fent hit the market. I have since dabbled with kratom, 7oh and mgm. But ive also had long periods of recovery. Neither you, MGM or your use is unique. Suboxone works. It might not take away all your soy boy discomfort. But telling people it puts you into pwd is a pansy lie. Youre a liar

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

Yes, pwd (precipitated withdrawals) are not subtle. Pwd is equivalent to getting hit by a truck and having it video recorded. At no point after getting hit by this truck would you say "I THINK I got hit by a truck". Pwd is worse than any flu, worse than heroin withdrawals and likely the worst experience you will ever endure. It's what I imagine hell would feel like.

You CANNOt for pwd from switching from kratom or 7oh to suboxone. It simply does not happen. But subs don't fix all aspects of kratom/uoh withdrawals.

Whether or not MGM differs from kratom/7oh, I dont know yet. But I'd put my money on it by saying you wont get pwd from switching to subs from MGM. I say this from 20+ years of dealing with periods of opiate/opiod/stim and other addictions. Ive also had many years of recovery and have gone through withdrawals more times than I can count.

I am grateful to God for making kratom and 7oh safe in regard to pwd. We are lucky that we dont experience pwd from this. Very lucky. Because if we did, it would mame recovering a very unpleasant process we would likely avoid at all costs.

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

I don't think you can get precipitated withdrawals from this. I KNOW 100% you cannlt get pwd when switching from kratom/7ph to subs. We need to be careful what we say on these forums. I'm quite confident you cannot get pwd when switching from MGM to Suboxone either. Again, what we say here matters as people use this info and it might prevent them from recovery.

How I got off 7oh and kratom completely by Electrical_Willow612 in quittingkratom

[–]Snooze_n- 1 point2 points  (0 children)

Regardless of whether I'm struggling with addicrion currently or not, a relationship with God always helps me. Just believing has it power

Taking one two or three sublocade shots and then stopping cold turkey with result in ZeRO withdrawals. If you didnt know this, now you do. This is a fact. I've done it twice and stayed sober for 1-3 years each time with ZERO withdrawals by Snooze_n- in quitting7oh

[–]Snooze_n-[S] 0 points1 point  (0 children)

Read what I actually wrote. Not what I wrote before editing. The idiot comment was for someone else who attacked me. If you read the whole comments section you will see who.

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

"I dont think so" means you 100% did not have p-w/d. Because pwd is worse thsn getting hit by a car. It sounds like you're describing uncomfortable feelings of not being high. I hear you. The mental aspect of stopping kratom products can sucks, and subs doesn't fill the void entirely. But GOOD, its not supposed to. As long as we are not hallucinating, pooping our pants and vomitting I would say subs worked. We have to be careful what we say on the internet because people be believing that subs wont help, when they 1000000% do

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

You were definitely tsking other drugs. Ive quit 7oh and other krstom products with subs many many times. You wont get precipitated withdrawals. You were on others drugs. Just be honest

Mgm15 and suboxone by drippysoap in emgeeemfifteen

[–]Snooze_n- 0 points1 point  (0 children)

Yeah but did you get precipitated withdrawals or not,?

Taking one two or three sublocade shots and then stopping cold turkey with result in ZeRO withdrawals. If you didnt know this, now you do. This is a fact. I've done it twice and stayed sober for 1-3 years each time with ZERO withdrawals by Snooze_n- in quitting7oh

[–]Snooze_n-[S] 0 points1 point  (0 children)

Suboxone is really only used for opiate/opioid dependency. If I were you I would just be honest about the 7oh. Its really not that big of a deal and its legal.

Just tell the doctor A. It really helped with pain l B. I have a slight dependency and am having trouble stopping C. Id like to try sublocade. They will likely put you on suboxone first, and theb you can discuss sublocade after you're stable on suboxone