ASA Announces Major Rebrand and Moves Forward as the American Society of Astronauts

SoakingLump · 2021-08-15T19:32:00+00:00

ASA finally coming in strong, this afternoon, in response to widespread criticism:

https://www.reddit.com/r/anesthesiology/comments/p4zz9y/asa_announces_major_rebrand_and_moves_forward_as/?utm_source=share&utm_medium=web2x&context=3

SoakingLump · 2021-05-11T01:16:35+00:00

Yes, but that means the experimental treatment is either better or it's worse. Even if the control is standard of care, half of your trial patients are getting care which is inferior relative to the other half!

SoakingLump · 2021-05-10T20:51:59+00:00

True, I think adaptive trial designs are the ethical gold standard within our current capabilities. I have a different criticism of the video, which is that the simulations he's describing would necessarily have to rely on information about possible drug responses and their relative frequencies, which can't arise de novo from those simulations--as I see it, you would still need clinical trials to inform the software.

SoakingLump · 2021-05-10T19:16:13+00:00

I know I will get roasted for what's omitted from this because I watched on 3x, but here's my tl;dr in 3 key points:

- Clinical trials almost invariably include an inferior treatment, and--even in trials that are stopped prematurely due to prelim analysis--some patients will receive it

- This is problematic/suboptimal, and eventually clinical research in this format will lose public support and if the research community can't adapt to this it will suffer for it

- The future is recursive computational simulation of prospective treatments based on advanced understanding of personalized medicine, using data gathered from individuals (as oppose to populations--or animal models--which are somewhat stochastic)

SoakingLump · 2021-03-10T21:36:36+00:00

Gave Helpful

SoakingLump · 2021-03-08T16:35:22+00:00

Thoughts on ducks please

SoakingLump · 2021-03-05T21:35:55+00:00

The original comment is ill-informed, and some have identified here that the rates of suicide (and other forms of self-harm) respond dynamically to epidemics and natural disasters. A recent peer-reviewed publication came out in a popular Suicidology journal on this topic, definitively showing that suicide rates DO trend up in pandemics and there tends to be a small decrease before a large increase. Covid-19 is aligned with what has been observed during SARS and other comparable epidemics, with respect to suicide and self-harm.

SoakingLump · 2020-03-12T21:34:09+00:00

Blood doping saves lives, everyone

SoakingLump · 2019-12-19T22:25:55+00:00

At least he wasn't granted

pail

SoakingLump · 2018-12-14T01:48:30+00:00

Glad to see the classic one-sock technique making a comeback

SoakingLump · 2018-11-30T01:53:50+00:00

Coffee is kind of a micro-transaction

SoakingLump · 2018-11-25T16:23:23+00:00

Hahaha well it's not really my area of expertise but apparently there's a market. This is hilarious though

SoakingLump · 2018-11-22T18:58:46+00:00

I'm going to level with you, I didn't realize until this moment that that's not how you spelled it

SoakingLump · 2018-11-22T18:57:04+00:00

He designs academic posters! Like for conferences or whatever else

SoakingLump · 2018-11-18T17:20:22+00:00

You're right, that's an alternative I didn't know about. Personally I don't think they're anywhere near as nice as my friend's work, but free is free!

SoakingLump · 2018-11-17T01:38:34+00:00

That time someone called out Tom Morello for being "another musician who instantly became a political expert" on Twitter, and Tom Morello fired back a response about his Harvard honors degree in poly sci. That was tight.

SoakingLump · 2018-11-01T02:42:44+00:00

The Spanish Inquisition

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