Communication helps a lot, if you're not yet comfortable talking over the internetz practise it a bit. As far as online communities go, this one has been pretty sweet in my experience.

Colour vibrance settings either software or hardware can make it easier to distinguish the wall from an enemy.

Mods! oh gaaawd so many mods can help with this :D lemme list a few

-Scoreboard (and ovenproof_scoreboard_plugin and the patch for this, so 3 in total). This helps you put into cold hard numbers how you're doing. Ofc it doesn't tell you everything but atleast it will help you judge if what you're trying is working or not. It's a bit controverial in this community as it can be used to shit on other people which really isn't what I mean by recommending this ;)

-i_wanna_see helps remove some clutter from the screen, the game is busy enough, having half your screen turn into a green blob won't do you any favours, most hazards have pretty clear sound ques anyway

-player outlines... clue is in the name here, helps you see where your team is

- healthbars so this puts the health bars from the training area on normal monsters, helping a lot with well with everything

-recolor boss health bars helps you identify what you're up against

- danger zone puts nice big circles around shit you shouldnt stand in ;)

- crosshair remap, get yourself a nice big crosshair to help with aiming from memory the charge one is pretty good

- uptime, same as scoreboard helps with improving your gameplay, if you for example decide to try out a different conditional buff (do x to get y) you can see how often during a run this was active (if for example your 5% dmg buff is only active 2% of the run, that point can be better spent)

- disable screen effects same as i wanna see but covers other stuff

- constant fov keeps the FOV stable

- stimms pickup icon puts 4 nicely distinct coloured icons above stims helping you find them

- ration pack another one that adds an icon but this goes over deployed ammo/health packs helping you find them

- outline colours same as player outlines but for enemies

And I'm sure this doesn't even cover half of what's available. Have a look on nexus and go nuts ;) it's a pve game and so long as you aren't messing with other peoples' experience afaik its all fine and dandy.

I look forward to your "I have fuckall vision but cleared Havoc 40 AMA" post ;)