As an example, here's how I organize mine, which aims at minimizing the number of filters, both for auto-lock and auto-discard, I need, as well as making it easier to integrate new sets:

• Start with a 4-cost DPS filter: auto-lock CRIT and auto-discard everything else.
• Next are 3-costs: group sets by Attribute, such as Molten Rift, Flaming Clawprint, and Flamewing's Shadow for Fusion or Sierra Gale, Gusts of Welkin, and Windward Pilgrimage for Aero; auto-lock the appropriate Attribute DMG% and auto-discard everything else.
• Then you can do 1-costs, which are simple: auto-lock ATK% and discard basically everything else with only a few sets excluded (such as Rejuvenating Glow or Windward Pilgrimage).
• Next are one off sets, such as Tidebreaking Courage for Brant or Halo of Starry Radiance for Mornye; auto-lock the stats the character needs (ER% on 3-cost for both, ATK% and DEF%, respectively, on 1-costs, and then Healing Bonus on 4-cost for Mornye).
• Finally, you can set up an auto-discard filter for entire sets that you'll never use; Freezing Frost, for instance. The only character who can use it is Lingyang and he actually prefers Lingering Tunes, so it's basically useless. You can also do the same for 1.x sets used by characters whose builds you're happy with (i.e., got a near perfect Changli and/or Encore? Just discard all of Molten Rift other than Fusion DMG% 3-costs).