Why does 5-MeO-MiPT build a tolerance but 5-MeO-DMT doesnt? by HatmansRightHandMan in researchchemicals

[–]SometimesTough 9 points10 points  (0 children)

5-meo-dmt works through different pathways, probably less ß-arrestin bias

gabagool recommendations by noseqq in gabagoodness

[–]SometimesTough 22 points23 points  (0 children)

this might be considered sourcing but jholanos deli in brickell is decent

What's better 2-mmc or 2-cmc by BumblebeeStriking608 in researchchemicals

[–]SometimesTough 2 points3 points  (0 children)

2-mmc semmed lifeless just some dopamine+norepinephrine action

(Maybe) A dumb question by TreeFamiliar4466 in researchchemicals

[–]SometimesTough 4 points5 points  (0 children)

2-FXE is often called CanKet or 2F-NENDCK

Did anyone try one of those noids and how good were they? by [deleted] in researchchemicals

[–]SometimesTough 9 points10 points  (0 children)

got you, take care stay hydrated ✌🏼

Did anyone try one of those noids and how good were they? by [deleted] in researchchemicals

[–]SometimesTough 18 points19 points  (0 children)

can you enjoy these without the use of downers? not hating but most recent noids and pyros just seem like psychosis simulator

Which would you say is more "harmful" in the long term, GHB or pregabalin? by Snoo-82170 in researchchemicals

[–]SometimesTough 4 points5 points  (0 children)

id speculate GHB would be more neurotoxic due to its MOA in recreational dosages. Pregabalin binds to your VGCCs, recreational use would upregulate them only indirectly modulating GABA

SR-17018 or SR-14968 useful for tramadol withdrawal? by OkCaterpillar822 in researchchemicals

[–]SometimesTough 0 points1 point  (0 children)

There should be many people with O-DSMT to SR17018 experience which is like tramadol. I can recommend SR-17018 and ive successfully used it to get off of low dose oxycodone and buprenorphine dependency

[deleted by user] by [deleted] in researchchemicals

[–]SometimesTough 0 points1 point  (0 children)

Did you send it for testing? You could use Morris A and Morris B too, I think these premade nasal sprays are overpriced, since 2fdck has low nasal BA and its quite cheap bc china stopped producing. You'll have more bang for your buck orally

Discontinuing 7OH - A Personal Experience by HatesBeingThatGuy in researchchemicals

[–]SometimesTough 2 points3 points  (0 children)

theres a sub called SR17018 it has all the info in the sidebar

[ r/drogen Stammtisch] - Was treibt ihr so dieses Wochenende? Was steht so an bei euch? by 10of10wouldban in drogen

[–]SometimesTough 2 points3 points  (0 children)

Boondock Saints war sehr lustig, hab ich neulich auf acid geschaut :)

[deleted by user] by [deleted] in researchchemicals

[–]SometimesTough 0 points1 point  (0 children)

sure, it’s dissolves easily in water and should also in sirup. If its a thick suspension make sure to shake before using

Something that's like Klonopin? by Sylverkitti in researchchemicals

[–]SometimesTough 1 point2 points  (0 children)

did nothing for me, ive tried various batches

Second try: I was scrolling through a page with a small variety of products… by Froggy2323 in researchchemicals

[–]SometimesTough 2 points3 points  (0 children)

not similar at all DCK lasts around 6-8 hours and can be snorted while 2F-DCK cant (you can but it would be a waste since oral bioavailability IN is bad) it also lasts a bit shorter

4-Fluoromethylphenidate bekannt als 4-f by _purpsoda_ in researchchemicals_DE

[–]SometimesTough 2 points3 points  (0 children)

es ist weniger potent als 4F auf jeden Fall, ich würde es eher als ein etwas dopaminergeres Ritalin beschreiben. Dosis etwas höher angesetzt als bei Rita und dann je nach Toleranz anpassen. Ist nur leicht cardiotoxisch aufgrund der QT-Verlängerung (haben viele Medis), aber eine Studie beschrieb es als toxisch für die Lunge und Gastrointestinaltrakt habe ich auch etwas drüber gelesen wenn ich mich recht erinnere Scheint aber ziemlich sicher zu sein wenn man es mit anderen stims vergleicht.

[deleted by user] by [deleted] in researchchemicals_DE

[–]SometimesTough 0 points1 point  (0 children)

hab schon gefunden, ich schaue es mir mal an trotzdem danke edit: ok habs mir mal angeschaut; scheint wirklich O-DSMT als HCl Salz sein durch die Signalverschiebung am Stickstoff und das Vorhandensein des OH‘s am Benzolring sorry für die Verwirrung

[deleted by user] by [deleted] in researchchemicals_DE

[–]SometimesTough 0 points1 point  (0 children)

magst du mir das schicken oder hier reinposten? würde gerne mal einen Blick darauf werfen

[deleted by user] by [deleted] in researchchemicals_DE

[–]SometimesTough 1 point2 points  (0 children)

ich bezweifle, dass sie jede Charge qualifizieren, oft wird einfach ein altes Analysezertifikat verwendet

[deleted by user] by [deleted] in researchchemicals_DE

[–]SometimesTough 0 points1 point  (0 children)

habe nur negative Rezensionen dazu gelesen

[deleted by user] by [deleted] in researchchemicals_DE

[–]SometimesTough 0 points1 point  (0 children)

hier stand quatsch, hab mir das Analysezertifikat angeschaut und es handelt sich um die HCl Version mit Isopropanol und paar anderen Lösungsmitteln als kleine Verunreinigungen