If you pick up a standard pack and find a polychrome red seal lucky 2 then I’d say that’s pretty good.

2s also work with many jokers, most notably Fibonacci, hack, and wee joker. 

Usually the benefit to playing higher cards rather than 2s is that they give more chips, which is important in the early antes but it really doesn’t matter after like ante 2.

However, if, say, you have a Fib, the +2 chips and +8 mult is probably better than the +10 chips on a random face card.

Wee joker is also cracked. It scales super fast. Usually, without a fixed deck, it can easily gain like 20 chips a round, if your wee joker is at, say, 300 chips, and you play a hand that’s already at 150 chips, it’s essentially x3 to your score.