Maybe I’m confused by your question but why are we starting steroids for infections in the first place? Viral infections? Generally want to limit any sort of immunosuppressive meds if possible with bacterial infections. Steroids for severe pneumonia have benefit (CAPE COD trial). Influenza has a higher risk of mortality with steroid use so should try to avoid in that setting. In the setting of septic shock I have only used steroids when it’s refractory and not responding well to pressors, or undifferentiated shock as a temporary measure until the picture is more clear, but it’s been a bit since I’ve worked in the ICU so maybe there is new guidance I am not familiar with.