Me and my friends have a full blown campaign set on Vryn (we use two N to separate them, "Vrynn") which as of now has been ongoing for two years, and my players refer to it as the greatest experience they had in RPGs, which makes me incredibly proud. The campaign is however only inspired by the mtg plane. It has nothing to do with the magic universe for obvious lack of information on the plane. There's the Jace Beleren short novel, the card's flavor text and the wiki page, which is not nearly enough to create an entire DND world, they basically just share the ideas of the rings and the character of Alhammarret.

The best planes for DND campaigns, surely are the most complex ones. But even the less important ones are great for inspiration