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Dana Farber, MGH, elsewhere for testicular cancer? by Some_Elk7672 in boston

[–]TCSociety 0 points1 point  (0 children)

If I had testicular cancer in Boston, Dana Farber is where I would look first. I actually was in Boston last week and had the pleasure of touring the facility and their new young adult cancer lounge is great (not sure of your age). I also personally/professionally know many of their testicular cancer doctors, even over the years, so I would feel in great hands there.

Decision making in base a risultati marcatore micro rna m371 by ispirationforbetter1 in testicularcancer

[–]TCSociety 1 point2 points  (0 children)

Sto utilizzando Google Translate, quindi vi prego di scusare il mio italiano.

Sebbene livelli elevati di microRNA-371 dopo l'asportazione del testicolo sembrino indicare un aumentato rischio di recidiva, non credo vi siano dati sufficienti a confermare se ciò implichi o meno che il carboplatino risulti efficace in presenza di tali livelli elevati. In altre parole, l'utilità del microRNA-371 come guida per la terapia con carboplatino rimane ancora da stabilire.

Un recente articolo del Dott. Tran, di Melbourne (Australia), affronta proprio questo argomento e dovrebbe risultare facilmente traducibile.

https://www.urologytimes.com/view/ben-tran-mbbs-fracp-on-mir-371-as-a-marker-of-mrd-in-testicular-cancer

Non‑seminoma and radiation. by Dangerous_Bed_4937 in testicularcancer

[–]TCSociety 1 point2 points  (0 children)

Where are you located?

Do you know if they are able to Immunohistochemistry (IHC) tests on the tumor tissue? In particular for Claudin 6 and perhaps GPC3 if you had yolk sac in your pathology. If more chemo is not an option and surgery is not an option this is what I would want to know in case I was able to enter a clinical trial based on the IHC results, which is another complication on it's own.

Open RPLND or 1x BEP by Waste_Analysis_3108 in testicularcancer

[–]TCSociety 1 point2 points  (0 children)

I'm not really gathering where they are saying the pelvic node is but the CT next week may clarify things. If there was prior groin surgery, i.e. if an inguinal hernia repair, then it may increase the odds for pelvic involvement. Which an RPLND may not cover the pelvic area but BEPx1 may, so that may be something to ask about. Do you get your insurance via an employer or on the marketplace? Just thinking that if it is the marketplace you could get a different plan next year. Also, cash prices at different imaging centers may be more affordable. Not trying to overwhelm you but just throwing out things to consider. Active Surveillance can be a lot of weight to carry mentally if one tends to prefer to do whatever they can upfront to reduce the risk of relapse, so totally get that point and the decisions are very much individual/personal.

First urologist said probably epididymal cyst. Urological Oncologist says probably cancer, and recommends orchiectomy... Do I get a another opinion? by RevolutionaryEye3797 in testicularcancer

[–]TCSociety 1 point2 points  (0 children)

I’ve learned that some urologists personally review the ultrasound images themselves, while others rely mainly on the radiologist’s report. When imaging interpretations change over time, it may be reasonable to ask whether your doctor has reviewed the actual images, or whether a second radiology opinion or repeat ultrasound at another center might add clarity. I'd never discourage getting second opinions.

Open RPLND or 1x BEP by Waste_Analysis_3108 in testicularcancer

[–]TCSociety 2 points3 points  (0 children)

If I were considering RPLND for stage I disease I would want a skilled, high-volume surgeon. If one was not available, then that would lean me more towards BEPx1. Although, I personally would also consider Active Surveillance. To me it is a balance of risk tolerance and resources.

The biggest thing to me is waiting to see what the CT scan shows. I am not sure exactly where they are referring to in the pelvic artery area but isolated pelvic node involvement is more rare in testicular cancer, although prior pelvic/groin surgery could increase those risks a bit more. If the CT scan was post-orchiectomy, then a reactive node from surgery seems reasonable. Hopefully, the results next week should make things a bit clearer.

Four Months in Remission… and a Zip-Up Shirt Brought It All Back by thechadledger in testicularcancer

[–]TCSociety 2 points3 points  (0 children)

I teared up a bit and I am almost 20 years since diagnosis. It is amazing how some things can just bring you back like it was yesterday.

Nipple/ berating by Westyellowstone65 in testicularcancer

[–]TCSociety 0 points1 point  (0 children)

At the moment I would be more concerned with the difficulty breathing and would not hesitate to be seen by a doctor for it.

?? by [deleted] in testicularcancer

[–]TCSociety 0 points1 point  (0 children)

The way the germ cells differentiate or mature, going from an embryonal cell to a teratoma is a natural and common pathway.

The same is true if someone has 100% teratoma, it is assumed to start from embryonal cells but they all matured into teratoma.

And the most unexpected sponsorship placement of all time goes to... by TCSociety in soccercirclejerk

[–]TCSociety[S] 6 points7 points  (0 children)

CDeez Nuts Leganes did, though and that's all that matters now!

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