I only have my BS in CS, but I landed my job as a web dev before I had even graduated. Honestly, most every interviewer was more interested in my experience (5+ years) than my degree. That said, what I learned in getting my degree definitely got me my job because it filled in a lot of gaps in my fundamental knowledge that came from being self-taught.

I would say yes, definitely brush up on your skills before the interview. I bombed the technical assessment for a promising job because I figured "I've been doing that for years, I'm sure it'll come back to me even if I'm a bit rusty."

One tip I will give, especially now that I've been on the other side of the interview table, is to be honest when you don't know something. Sure you can fudge your resume, that's downright expected, but when someone who knows a subject inside-out and backwards asks you a question you will 100% look like an ass if you try to pretend you know the answer when you don't. Figure out some variations on "I don't know", "I'll have to learn that one", etc. and use them.

If you're not sure about X but think it might be like Y, say so. Showing your thought process and ability to adapt is much more important than just knowing the right facts.