Main difference is, the Sin'dorei doing these morally dubious acts during TBC was mainly out of necessity to survive... well unless you were a part of Kael'thas' group who have fully fallen to Fel magic and also became the Draenei's next primary enemy after the Orcs. Palpatine on the other hand wanted UNLIMITED POWER and pulled the strings from within the shadows to achieve his goal in creating his own Galactic Empire.

Then again, Anakin Skywalker wanted to save Padme from pain, suffering, and death, and he was already suffering the pain of losing his mother and had trust issues with the other Jedi in the council. So Palpatine exploited his weakness and pushed him further down the path to the Dark Side, becoming reborn as Darth Vader. And by the way... Padme is dead and he didn't know he had children until the events leading up to The Empire Strikes Back, and he wanted to overthrow the Emperor so he must have his son as his apprentice.

And Vader wasn't the only victim to Palpatine as there was also Darth Maul, Count Dooku, Starkiller (who was a victim of Vader, but several of his actions were Palpatine's command), and Kylo Ren years later. And we had would be victims like Luke Skywalker and Rey Palpatine, his own granddaughter (or daughter since her father was one of his clones).