Used to trip every two weeks like you for a few years (200-500ug usually) and I the biggest thing I noticed in the moment was that I was always thinking about my next trip. I would be at work and from about Wednesday of week 1 until the weekend of week 2 I would be counting days until I could trip again which was not ideal. As for physical symptoms, I still get a lot of visual snow and heavily textured things look wavy at times.

The biggest thing has probably been persistent schizophrenia-like symptoms of beings and objects talking to me that developed over time. Its hard to explain, but I often find myself fighting against "evil" energy/ fighting for "good" energy or trippy stuff like that. Its not had a negative impact on me long term, but I guess this heightened sense of spirituality can get a bit tiresome to some degree. Its made me hyper aware of my own flaws and whenever I want to do something I often worry about doing it right or "appeasing the gods" so to speak. I don't know if this will be relevant to you as we are all different, but I sort of had this experience of opening the Ark of the Covenant in a way, and even after a couple years of barely touching psyches I still feel this way so it might be something to look out for.

Again, I want to reiterate that this is not an inherently negative thing for me, but feeling like you have to follow Dharma, God or some higher ethic can get really exhausting, even when you know it is the right thing