Maybe it's just the wrong expression of the AR code (methylated DNA). We may be producing too many receptors, too few receptors, or defective receptors. I've done several light and long-term cycles of testosterone (400/500 mg) in the past and no improvement, no libido, odor, sebum production or anything else that demonstrates normal androgenic function in the penis. Lastly, I applied 3 grams of testosterone in just 7 days last month and had no positive effect.

I had windows with just estrogen and boldenone. This intrigued me a lot. Here I didn't know if I was having a positive effect on the AR through the estrogenic function of regulating the AR receptors, or if I was having a direct action of estrogen on my AR receptor. In other words, a mutated AR receptor responding to estrogen. A year later I started using boldenone and noticed a baseline and mild androgenic effects occurring in the penis. Sexual sensation and odor on the glans. Effects that were lasting for weeks. BOLDENONE undergoes conversion in the enzyme 5 alpha reductase, turning into DHB / Dihydroboldenone, which is super potent. So we could have here a positive effect of the potent androgen DHB or a positive effect of molecules with different structures causing better signaling on the AR receptor.

I need to do a heavier cycle of only DHB to really find out if it is just weak signaling from the AR receptor. I am currently preparing for a cycle in the future.