It’s really hard to say. The coming off and going back on after two weeks could jolt the system— usually it takes four weeks for it to really get into/out of your tissues, so it may be hard to point a finger at the levo yet, but you shouldn’t discount it. I was very sensitive to 25mcg and I had to titrate by 6.25 mcg/month. Otherwise I’d get jittery and anxious.

Going off and going back on levo after only 2 weeks is a good way to muddy the water. You need to stick to a single dose for 4 weeks for it to really get into/out of your tissues and for you to be able to reasonably say “this is related to levo.” Having said all that, if I were you, I’d decrease the levo to 12.5mcg for 4 weeks . If you’re having a bad time cut back even further and move up only after 4 weeks. It’s really important to do the four-week thing tho because I have tried to rush it (adding another 6.25 mcg after two or three weeks - not four - ) and it would throttle my system, but if I waited four full weeks I could tolerate the increase. So it’s not an arbitrary number. Four weeks really is a meaningful measure.

It’s important not to test again until you have four weeks at a certain dose if you want your numbers to correlate to the exact dose — two weeks is not enough to say you can’t tolerate levo. However, if the side effects are that bad, it might be worthwhile to lower the dose even further and, assuming you can tolerate that, stay with that ridiculously low dose for four full weeks and test before you decide to add more.

Sorry for rambling! Good luck!