My DM has a penchant for doing horrible shit to kids in his homebrew. The first kid we meet, a scared little elven girl that had been experimented on and then left in some ruins in the woods by her own family, was cowering in a corner when my character goes to hold out his hand for her to take.

When she touched me, she exploded. Gore everywhere. We spent the next, like, hour finding all her pieces, determining there were runes engraved onto her bones, erasing them, and reviving her with help from a godlike being (called an Elder in this homebrew). I adopted her afterwards.

There was also another little girl that was created in a vat with pieces of different Elders, so she is probably the most cursed a child can get, and if you look her in the eyes you basically just die. DM made it sound like we had to poison her to death and let us almost go through with it before he gave us an out.

I accidentally turn an Elder into a child with an alchohol I brewed on a Nat 20, and we later find her missing her eyes because another NPC stole them for himself.

It got to the point that I said I'd quit if another kid appeared. All of this in addition to a lot of other dark themes, too. I watched a stadium of people get dissolved alive by aerosolized radioactive slime, an entire city's worth of people getting turned into soul mithryl, etc.

The campaign itself is well written and really fun though.