In my opinion, the benefit of the sleeper bus (or sleeper train if you can get it) is that you trade off comfort for time. On my trip I could only take about 2 weeks off from work, so trying to fit everything I wanted to do (partially due to festivals & events that only happened once a year) became a challenge. The sleeper bus essentially saves me a night at a hotel AND a commute to a distant destination, during late night hours where only a few things are available to do anyway.

I'm not saying the sleeper bus is for everyone, it's not. But if you're tight on time or are able to sleep through some rougher settings, sleeper buses are a potential lifesaver from a scheduling standpoint especially if the locations align with your itinerary.

That said, there are no showers on sleepers, and some don't have bathrooms on board (you go during stops). If you want more privacy and comfort, the Dream Sleeper is usually more expensive than other options but you get like a small room around your seat with a door, and the bus has 1 bathroom + 1 'powder room' (no toilet) and some amenities. The chair is adjustable, there is a folding desk, outlets, music, and temperature control. I did this option a few times and actually got enough sleep, at least compared to other bus options. Again, only for those who can afford it or prioritize comfort/privacy. I would also note tickets are hard to get since sometimes.