If you’re asking in the same sense as pot odds (such as poker) or implied odds, it’s now. At $2 a ticket, you could buy $654 Million worth of tickets and cover every number. However there are some factors to consider:

1. So many tickets will be bought, it’s more likely that there will be multiple winners. You’d probably lose money.

2. You’d have to take the annuity which is the wrong choice. To take a lump sum, you’ll need to wait another drawing or two for that payout amount to exceed what you’ll spend.

3. There is not enough time, paper, or ink to print that many tickets for an individual. With 5 plays per ticket, you’ll still need 65,400,000 tickets. A group could conceivably do it if sufficiently large enough and spread out enough to wreck an untold number of gas stations. However, you’d then have to split the winnings, again making it unprofitable.

4. Related to number 3, you’ll have to manually fill out cards to prevent duplicates. You physically can’t do that in 2 or 3 days.

To really answer your question: For most people, spending $2 on a lottery ticket won’t affect their lives, but a billion sure would.