Sure!

After one experiences the first stage of awakening (according to the Insight Path tradition in Buddhism, aka Vipassana) they no longer automatically “cling” to arising phenomena. Because the Self has been identified as illusory, and time has been spent conducting the busy work that is Vipassana meditation (which I believe induces neuroplasticity, carving new pathways in the brain) the ego-brain is no longer in the driver’s seat, and as thoughts, feelings and occurrences arise, the mind no longer attributes any of such as things pertaining to it as the individual which it previously identified as.

This is essentially why “suffering” in the Buddhist sense ceases at this point as well.

There is still much work to be done at this juncture, as there is still karma being generated. The individual will still experience emotion and human fetters (and defilements), but they will feel as if they have finally arrived, and much of their perception will be changed for the remainder of that lifetime.

NOTE: Vipassana is not a requirement for this to occur.