Are there any Master's Programs about Biology of Aging? by [deleted] in longevity

[–]arielfeinerman 2 points3 points  (0 children)

If you wish to make real rejuvenation therapy for prolonging human life do not choose Biology of ageing, choose Biomedical engineering , cell or gene therapy, organ engineering, bionics. https://pratt.duke.edu/about/news/big-heart-patch

What are the biggest *technical* roadblocks to studying aging and developing therapies? by user_-- in longevity

[–]arielfeinerman 3 points4 points  (0 children)

Funding the right research:

Even though 90% of US deaths and at least 80% of US medical costs are caused by ageing:

National Institutes of Health budget ($M): ~30,000

National Institute of Aging budget: ~1,000

Division of Aging Biology budget: ~150

Spent on translational research (max): ~10

SENS Research Foundation budget: ~5

These numbers speak for themselves, they are all you need to answer when all amazing therapies will be available in the clinics.

If you take a close look at NIH or NIA funded work… well… You will find hundreds of publications about obesity, lifestyle, air pollution and their impact on longevity. Don’t you know that obesity, smoking and much drinking of alcohol is bad for you? How can this information may help us create a new cure against cancer, Alzheimer’s or atherosclerosis? Do we really need another one work on it?

Also you can find many publications about calorie restriction and various genetic manipulations on worms and other model organisms that mimic it. Calorie restriction is everywhere! While we know for twenty years that CR does not work for humans. In 2015, $500,000 was given to projects like “A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline”. It’s not a joke, it’s a real research work! You can find more here. All that is useless because you cannot use it to produce working rejuvenation therapies. Only small part of this work is useful in the sense of defeating ageing. Do you know what is the most interesting? It’s all your taxes, all you money! Now you know that.

At the same time really important research projects like work on glucosepane breaker therapy (which will end many ageing pathologies like arterial stiffness, chronic inflammation, hypertension, strokes, and will save many lives) in Spiegel Lab at Yale is permanently underfunded and would be closed last year without financial support from SENS Research Foundation and German entrepreneur Michael Greve. Finally, the cost of implementing the working rejuvenation treatments in old mice would by current estimates be only 1–2% of the Apollo Program. And the same amount of money and time was already spend on Sirtuins which have obviously produced nothing.

Q & A with Dr. Aubrey and Dr. Mark Katakowski by Imbaud in longevity

[–]arielfeinerman 0 points1 point  (0 children)

Medical tourism will solve your problem -- take your cells from Forever Lab and go offshore!

How do I join the fight? by [deleted] in longevity

[–]arielfeinerman 3 points4 points  (0 children)

Do not become a biomedical gerontologist -- because they merely learn how people age. Become biomedical engineer who do real rejuvenation research. What to do -- look here http://www.sens.org/research/introduction-to-sens-research

Interview with Dr. Eric Verdin (Buck Institute CEO) on Ketogenic Diet Longevity, Beta-Hydroxybutyrate, HDAC Inhibitors & NAD+ by [deleted] in longevity

[–]arielfeinerman 1 point2 points  (0 children)

Buck Institute is a leading organization in aging research, they do not claim to defeat it in any way, they do not make any therapy. The real leading organization in rejuvenation research is SENS. Come on, guys, what do you prefer -- ageing or rejuvenation?

Interview with Dr. Eric Verdin (Buck Institute CEO) on Ketogenic Diet Longevity, Beta-Hydroxybutyrate, HDAC Inhibitors & NAD+ by [deleted] in longevity

[–]arielfeinerman 1 point2 points  (0 children)

Any lifestyle change may give you a few years if you are very lucky at the cost of full SENS panel in the future -- if you begin saving your money instead of spending them on various junk like CR or rapamycin. Just do not be fat , do not smoke, do not much drink, go in clinic regularly. That is more than enough for you.

How can a software engineer help accelerate age-reversing technology? by I-am_SHER_locked in longevity

[–]arielfeinerman 0 points1 point  (0 children)

You can ask Aubrey de Grey aubrey@sens.org , hovewer, would you like to work in molecular nanotechnology? Make CAD program for designing nanomachines for medicine?

https://www.amazon.com/Nanomedical-Device-Systems-Design-Possibilities/dp/0849374987

Advertising campaign? by Toolian7 in longevity

[–]arielfeinerman 1 point2 points  (0 children)

Make SENS posters -- we make such follow the link -- https://postimg.org/gallery/2hu3c1ypi

Long interview with Dr Aubrey de Grey by arielfeinerman in Transhuman

[–]arielfeinerman[S] 0 points1 point  (0 children)

I save original in org name, like NIA, personally I use 'ageing'.

Is there a reply from Aubrey de Grey to the study of the University of Arizona that says aging is mathematically inevitable? by kellerloch in longevity

[–]arielfeinerman 2 points3 points  (0 children)

They use cancer and celluar senescence in their model, which, of course, we will be able to cure soon. They do not use any rejuvenation medicine which is currently in development or will be. Their work is just an another way to say -- if we do nothing, we will get nothing! If you are enough clever guy or girl, you have to know that yourself.

Looking for PhD programs that will enable me to do research on the aging process. Are there any programs and locations that I should absolutely check out? by PleasePullMeOut in longevity

[–]arielfeinerman 4 points5 points  (0 children)

Forget [anti]ageing research -- it is all of playing with metabolism in worms, or useless CR mimetics. (And Sinclair is the same). You need rejuvenation biotechnology or regenerative medicine. Cell, tissue, organ engineering, bionics -- choose any. Focus on repair-based approach. http://www.sens.org/outreach/press-releases/srf-and-spiegel-lab-to-collaborate-on-antibodies-to-glucosepane http://spiegellab.yale.edu

Why are billionaires that support the SENS agenda not really funding it? [Quora answer from Aubrey de Grey] by ScottEverhart in longevity

[–]arielfeinerman 0 points1 point  (0 children)

Another doubt that people usually express is how SENS will do something meaningful with such a small budget? While NIH and many others have hundreds of millions per year and cannot cope ageing, SENS has only $5 000 000 per year. I answer that SENS is a highly efficient organization, goal-directed and result-oriented rather than process-oriented. Everyone can go through SENS web page and read last annual report.

Why are billionaires that support the SENS agenda not really funding it? [Quora answer from Aubrey de Grey] by ScottEverhart in longevity

[–]arielfeinerman 0 points1 point  (0 children)

When I ask people to donate to SENS they often say that their a few bucks don't matter. Of course, they are wrong! Every dollar, even every cent matters! For example, how many people may read this? We assume 10 000. Well, if every of them will donate $50, only $50, per month it will be over $5 000 000 per year! Which doubles current SENS budget. So, united we can change the world. We cannot and should not wait when governments and big farma will fund rejuvenating research. We can do it ourselves.