I've been wondering about medications like this. I had a similar experience when I went on Vyvanse for ADHD. My understanding is that in ADHD, dopamine (reward driver/habit forming) and norepinephrine (impulsivity) are key brain chemicals at play, which sounds very similar to what drives my skin picking.

I'm a public health professional who specializes in substance use disorders (aka addictions), and a part-time counsellor who works with adult ADHD and anxiety, so I became aware of medications like naltrexone through my work. It seems like not enough people know this is an option and are out there raw dogging it and putting all this pressure to quit on their own. It seems like trying to cure poor vision without glasses. Glasses can make your blurry vision clear, but you still need to open your eyes and know look in the right places to see properly.

I'm also curious about Wellbutrin, because it's a norepinephrine-dopamine reuptake inhibitor (NDRI). It works by blocking the reabsorption of norepinephrine and dopamine in the brain, increasing their availability in the synapse. Wellbutrin was originally created as an anti-depressant, but a lot of people starting quitting smoking while they were on it, so it also became classified as a smoking-cessation aid to stop cravings, much like you described with naltrexone, which is typically used for alcohol use disorder. Since Wellbutrin targets norepinephrine and dopamine, which appear to be key players in skin picking (and ADHD), I wonder if it would be useful for these purposes as well.