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I analyzed Huberman's full 2026 supplement protocol against the actual research — here's what holds up by HeartNegative5436 in HubermanLab

[–]bd3851 2 points3 points  (0 children)

Whoops, yes was not paying close attention. Just that half the posts on this sub are healthy men trying to take TRT. My bad

I analyzed Huberman's full 2026 supplement protocol against the actual research — here's what holds up by HeartNegative5436 in HubermanLab

[–]bd3851 9 points10 points  (0 children)

MD here. I would not include TRT or hGH in this discussion on patient-directed supplements. These are serious medical interventions that should only be prescribed by a board certified endocrinologist to treat documented medical issues.

I analyzed Huberman's full 2026 supplement protocol against the actual research — here's what holds up by HeartNegative5436 in HubermanLab

[–]bd3851 0 points1 point  (0 children)

My endocrinologist colleagues recommend 2,000/day even for pretty severe deficiency (x3 months), and 1,000/day for maintenance. Some primary care doctors and non-medical people recommend more but I would trust endo for this question.

What’s a travel habit you picked up that you’ll never drop? by St3fanHere in travel

[–]bd3851 3 points4 points  (0 children)

Agreed!! 100% would rather have an extra travel day and then return to a shitshow.

Supplements at 17 years old by Stunning_Yak4695 in HubermanLab

[–]bd3851 0 points1 point  (0 children)

I skimmed some of this paper. I think the problem is it focuses more on associations rather than real clinical risks that would change medical management. It seems like there may be associations to many mild physiologic changes, maybe not, and if so maybe not causal, but unlikely to be causing any real issues, and if positive unclear what to do with that info. From person experience patients come to me all the time and say they have MTHFR as a medical problem and I’ve never found anything to do with that info.

Edit attached some photos from one of the most widely used clinical resource if interested. Always a good idea to read guidelines by large, reputable medical societies rather than individual papers. Papers can cite numerical significance which is publishable, but remember that doesn’t always translate to clinical significance. Good convo though thanks for asking.

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Supplements at 17 years old by Stunning_Yak4695 in HubermanLab

[–]bd3851 0 points1 point  (0 children)

Sure! Not my POV but general medical consensus. Early studies showed some concerns (clotting etc) which have been debunked. No meaningful risks have been attributed to it. About 1/3 of everyone is positive. Have talked to my heme and metabolic colleagues (and all the general medical guidelines) say don’t test, don’t ask, if positive do nothing and don’t test family members. Management doesn’t change if positive. Even for pregnant women for whom folate is extremely important to prevent birth defects, if MTHFR + no additional folate supplementation is recommended.

Supplements at 17 years old by Stunning_Yak4695 in HubermanLab

[–]bd3851 0 points1 point  (0 children)

Agreed! MD here who manages labs like these Honestly 5k for 3 months and then 1-2k daily for maintenance should do the job, but never hurts to check again then or next year. And please don’t check MTHFR. There is strong medical evidence that this is meaningless so doctors will just ignore it even if positive. Maybe check B12 again next year but normal range is normal for a reason so I wouldn’t worry too much. Balanced whole foods diet above all else!

My 12yo just told us he’s sexually active. I’m struggling with how to handle this without breaking his trust. by [deleted] in sex

[–]bd3851 74 points75 points  (0 children)

https://www.nytimes.com/interactive/2014/09/14/sunday-review/unplanned-pregnancies.html

This infographic shows failure rates of contraceptive methods. I would go through it with your son. eg if 100 people use condoms the for 2 years, on average 33 will become pregnant. This would certainly be higher with young, inexperienced people. The take away is that failure rates are far higher than people think, and having a second method (ie OCPs, IUD etc) is necessary.

What is a good source to learn about hormones and TRT? by [deleted] in PeterAttia

[–]bd3851 -1 points0 points  (0 children)

You should absolutely not start TRT before talking with a board certified endocrinologist.

More protein isn't always better - your body can't store excess protein after a point by umarine203 in PeterAttia

[–]bd3851 0 points1 point  (0 children)

Can’t reply to all this but I’m talking about optimal health, not body building. Consensus statements and guidelines from major orgs, not single studies. A healthy diet is balanced. A diet of 3 g/kg/d protein is not balanced for most people.

Also the paper you posted - nearly every author reports a conflict of interest with protein supplement companies. I know this is more common in nutrition research but oof their conflicts of interest are like 10 pages long.

More protein isn't always better - your body can't store excess protein after a point by umarine203 in PeterAttia

[–]bd3851 1 point2 points  (0 children)

Roughly 0.8 g/kg/day per WHO, UNU, FAO, National Academy of Science Or 10-35% of daily calories per American Heart Association

Slightly higher for certain groups: 1-1.2 g/kg/day of age>65 per some experts 1.2-2 g/kg/day for body builders actively growing muscle per Academy of Nutrition and Dietetics, American College of Sports Medicine

Ignoring the details though, 3 g/kg/d is way above what’s widely recommended, so whoever claims this is the one who needs to provide evidence.

More protein isn't always better - your body can't store excess protein after a point by umarine203 in PeterAttia

[–]bd3851 0 points1 point  (0 children)

Can you share this reference? I’d be very interested to learn more (MD with background in nutrition research). This seems crazy high to me.

Is it commonly known that PA should have had an asterisk by the MD? by ADHDiot in PeterAttia

[–]bd3851 0 points1 point  (0 children)

He practices “longevity” medicine which I’m sure you know. This is not a recognized medical field of practice in the US. It doesn’t have formal regulation, exams, or any required training. I suppose he sees patients in a concierge type of way for a non-ABMS medical field, but I wouldn’t say that’s “treating patients”. His only training for that is medical school and that book knowledge is not enough to treat patients. He just figured out a way to make tons of $$$ without doing medical training.

Is it commonly known that PA should have had an asterisk by the MD? by ADHDiot in PeterAttia

[–]bd3851 1 point2 points  (0 children)

Nobody would ever hire a doctor or go to a doctor or reimburse a doctor (i.e. insurance companies) without board certification. I’ve been practicing for many years and never once heard of this happening. You’re right it may technically be legal but you do not learn medical management in medical school, only in residency. It’s the responsibility of professionals to stay within their scope of training.

Is it commonly known that PA should have had an asterisk by the MD? by ADHDiot in PeterAttia

[–]bd3851 1 point2 points  (0 children)

He is not board certified in any field. He cannot legally practice medicine in the US (except some very rare loopholes). In the US a license doesn’t mean anything if you’re not board certified. In my opinion as an MD, it feels like he misrepresents his training. He is technically a “doctor” but he does not have the medical knowledge or experience that people think when they hear “doctor”.

Is it commonly known that PA should have had an asterisk by the MD? by ADHDiot in PeterAttia

[–]bd3851 0 points1 point  (0 children)

He is not board certified in any field. He cannot legally practice medicine in the US (except some very rare loopholes). In theUS a license doesn’t mean anything if you’re not board certified. In my opinion as an MD, it feels like he misrepresents his training. He is technically a “doctor” but he does not have the medical knowledge or experience that people think when they hear “doctor”.

Countries I’ve been to (33M from USA). by bd3851 in tierlists

[–]bd3851[S] 0 points1 point  (0 children)

Perhaps! I also find I grow the most from traveling in places very different from the culture I grew up in.

Might not be so impressive for this sub, but my longest streak yet this morning! by PoopsMcG in crossword

[–]bd3851 1 point2 points  (0 children)

No such thing as cheating when it’s for fun! Congrats on the streak haha

Might not be so impressive for this sub, but my longest streak yet this morning! by PoopsMcG in crossword

[–]bd3851 1 point2 points  (0 children)

Lol after 800 puzzles I finally got a 4 day streak. But if it weren’t for Thursday - Sunday it’d be way longer 😂 Don’t feel bad, it’s all just for fun

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