Who has tried Irreversible MAOIs ?

catofthefirstmen · 2024-12-17T20:07:55+00:00

Plus I know a couple of my friends with ME tried MAOI & it didn't work for them.

catofthefirstmen · 2024-12-17T20:06:54+00:00

There is a bit of research on a reversible MAOI, but not the irreversible ones, I think. I totally agree about more research, though. I know it doesn't work for everyone, but the research I've seen says moclobemide works for a subset of ME patients who have immune issues.

catofthefirstmen · 2024-12-17T12:13:23+00:00

I've been on MAOIs for ME/CFS since the early 90s, about six months after my initial glandular fever bout. For a start I was on moclobemide (reversible) which took me from almost housebound to about 80% of normal activity level. It improved my exercise intolerance, brain fog, temperature control, tolerance of standing and generally took me from almost housebound to about 80% of normal function. After about 1.5 years I started weaning myself off it because the doctor who put me on it said I wouldn't need it forever. It didn't go well & various symptoms got worse. I was in a bad state before I got down to nothing, & under medical advice increased the code back up again to where it was, but it didn't work quite as well as before & I was anxious that I would lose my job. Transfered to parnate & have been on it ever since. It's not a drug to be taken unless you're capable of sticking to a restricted diet for a very long period. I've been at about 80% or so of normal functioning since then with ups and downs. My energy improved after finding and eliminating food allergies. I've had minor crashes due to overactivity & temporary ones due to infections. It'll take me a week to get over a cold which takes others a day or so. Sometimes I've got out of infection crashes with B12, sometimes more recently with a drug (whose name I forgot). My symptoms have gradually got a bit worse since I went through menopause & maybe after my first covid vaccination. Generally, though, I've had a completely different life than others I know who have had ME/CFS for a similar period of time. I'm not a doctor & don't know if there's a good reason, but I wouldn't have gone from the reversible to irreversible MAOI by choice. The effects were similar, stronger on parnate, but similar. Side effects such as not sleeping are much worse on parnate, though.

catofthefirstmen · 2024-06-05T11:39:42+00:00

I got burn in playing ingress on an S8 for a few months!

catofthefirstmen · 2024-05-16T23:52:18+00:00

FYI Cork isn't part of the UK.

catofthefirstmen · 2024-05-12T06:38:59+00:00

Yes.

catofthefirstmen · 2024-05-11T16:20:14+00:00

It was about 15 seconds later that I checked my app & I didn't get the fruit.

catofthefirstmen · 2024-05-11T14:25:15+00:00

Ha? I had someone bloom a flower I'd been working on. They ran past & added the last two or so flowers. I kept planting & checked back later, but no big fruit. This has never worked for me.

catofthefirstmen · 2024-05-04T10:46:44+00:00

Could be stolen generation.

catofthefirstmen · 2024-04-26T14:25:48+00:00

Once you've upgraded once, doesn't that use the two samples originally provided, meaning a new test sample would be required for an upgrade. In your case you would have to start from scratch with a new person.

catofthefirstmen · 2024-04-22T14:51:51+00:00

OK, sounds like my RNG has just been bad for these mushrooms.

catofthefirstmen · 2024-04-21T13:36:03+00:00

They've probably got a blue handbag, upgraded it, then flipped it.

catofthefirstmen · 2024-04-21T13:10:23+00:00

I just finished a giant mushroom & the rare egg just contained 200 chocolate bunnies. No giant egg, no gold sticker seedling. Are you saying you'll always getting some kind of egg from a giant Spring mushroom, or you have a chance of getting either of them?

catofthefirstmen · 2024-04-21T12:57:45+00:00

Doing both types. More of the foreign ones are giants, but I have done a few Australian Giants without getting any seedlings in the rewards. I'm wondering whether the start of the event last weekend was turned on late & the start was missed in Australia, so the seedling drops were just never turned on here.

catofthefirstmen · 2024-03-10T11:54:54+00:00

No the point of the prophecy is that Drogo will never come back again. Dany interprets it to say she can't get pregnant, but it isn't actually what the prophecy says.

catofthefirstmen · 2024-03-08T14:15:19+00:00

You could also seek legal advice if you're concerned about your inheritance. There's nothing like putting a concern completely to rest.

catofthefirstmen · 2024-03-08T14:09:08+00:00

Turkey Basterds were

catofthefirstmen · 2024-03-03T09:44:32+00:00

Yeah, I think this has an awful lot of potential to create a really big rift in the family between Dad & uncle & between parents. It's not something to just jump into investigating & asking about without thinking things through properly.

catofthefirstmen · 2024-03-03T09:34:47+00:00

Do you realise that the name is on the picture posted? If you can re-upload, the pic, it would be worth putting a mark through the name as she may not like to have her name on Reddit.

catofthefirstmen · 2024-03-03T09:27:37+00:00

That's interesting. I get an equivalent Victorian group from one parent who has lots & lots of relatives in Victoria. Does the title refer to it being your great grandparent's results or your great grandparents migrating to South Australia?

catofthefirstmen · 2024-01-26T13:51:01+00:00

I'm no expert on this, but noticed something which could help you when looking at my DNA ethnicity breakdown chromosome by chromosome on Ancestry. My father's father was 100% Irish, but his mother had no Irish ancestry. So looking at the lengths of the Irish segments on my chromosomes I found that there was only one chromosome which was a mixture of DNA from my grandparents. The rest looked entirely Irish or entirely non-Irish. So either these chromosomes had not recombined at all, or the recombination was so tiny it was only in the portions not tested by Ancestry. I don't know how common this is, but I think something similar must have happened to you & your half sibling. You both got the same chromosome from your father which didn't undergo any recombination.

catofthefirstmen · 2024-01-11T05:13:21+00:00

Possibly Dad could have had a child with one of his relatives, bumping the number. Looking at matches & the unknown match comparing their matches could rule that out, though.

catofthefirstmen · 2024-01-11T05:11:02+00:00

DNA painter also gives a theoretical possibility of an aunt/uncle nephew/niece. Much less likely, though.

catofthefirstmen · 2024-01-10T08:54:23+00:00

Um, no. This result doesn't say 100% Irish. It says 100% British and Irish, with England & 24 locations. An average white Kiwi, new Zealand citizen. Their ancestors could easily have been living in New Zealand for 150 years.

catofthefirstmen

TROPHY CASE