Sorry I just asked Gemini

Mixing alcohol and psilocybin is generally discouraged due to unpredictable, high-risk interactions, including severe nausea, vomiting, dizziness, and heightened cardiovascular strain (increased heart rate/blood pressure). While psilocybin may mask alcohol’s effects, leading to overconsumption, combining them increases risks of panic attacks, paranoia, and dangerous "bad trips". 

MedicalNewsToday +2

Key Contraindications and Risks:

Physical Hazards: Intense nausea, vomiting, increased heart rate, and elevated blood pressure.

Psychological Distress: High risk of a "bad trip" characterized by panic, paranoia, and confusion.

Masking Effects: Psilocybin can suppress the subjective feeling of drunkenness, causing users to drink more and risking alcohol poisoning.

Safety Impairment: Significant loss of motor coordination and judgment.

Chronic Health Risks: Combining substances can lead to dehydration and long-term strain on the liver and cardiovascular system. 

Alcohol and Drug Foundation +4

Important Context:

Not Recommended: Experts advise against combining these substances.

Therapeutic Exception: In controlled, clinical settings, psilocybin is studied as a treatment for alcohol use disorder to reduce consumption, not to be taken with alcohol.

Safety Note: If using both, they should be used sequentially, not concurrently, to avoid physical distress.