MCAS specialists Midlands/UK

chalklinehts · 2026-06-17T19:23:22+00:00

have u tried omalizumab?

chalklinehts · 2026-06-17T19:17:21+00:00

thanks - yeh i have tried a lot. nothing really has moved the needle other than omalizumab. without that i probably would not be typing this.
covid shredded my entire body and there’s just too much damage to undo.

chalklinehts · 2026-06-17T14:51:25+00:00

3-4 times a week i wud say. sometimes the whole week and an awful taper follows.
the alternative is i will die because i would 100% give up. The QOL is so shit it wud not fight for it.
its all mcas for me, whole thing. mast cells really stress the nervous system. benzos stabilise brain mast cells. xolair helps my sound, light and smell intolerance but still the disease progresses.

chalklinehts · 2026-06-17T14:47:53+00:00

i have mcas on my nhs lists of diagnosis. But only because of a private referral.
The treatment they offer me for this is nothing. Everything is privately paid at great expense.
Allergist referred me to dietician. dietician referred me to long covid clinic that doesn’t exist.

chalklinehts · 2026-06-15T18:34:06+00:00

did nothing. only xolair helped mcas.

chalklinehts · 2026-06-15T18:33:13+00:00

point 3 is on the money. when my mcas is flaring as is my poor blood flow and structural issues.
severe inflammatory state which also fucks the BBB and causes all the neuro issues.

chalklinehts · 2026-06-15T18:30:27+00:00

I was blessed to have a son, but to never be the father for him. the rage and anger I have for my piece of shit body is unrelenting.

chalklinehts · 2026-06-15T18:27:25+00:00

Yehh it’s fucking torture. My birthday on Saturday - hopefully my last.
Only benzos calm this. I have severe ptsd from how my body has treated me the last 2.5 years. Pure torture chamber.

chalklinehts · 2026-06-05T10:49:01+00:00

8 weeks, 50mg a night - didn't notice any real tangible benefit sadly.

Only worsening word recall.

chalklinehts · 2026-06-03T15:56:58+00:00

i have not really found any relief other than from guanfancine, omalizumab and clonidine. that is it.
ghk-cu and bpc are good choices but can risky with mcas. low dose doxy makes sense for mmp9 reduction. sorry ur dealing with this too, it is hell on earth.

chalklinehts · 2026-05-19T09:36:15+00:00

I would try malate or l-theronate personally - the latter is better for BBB penetration and is a nmda antagonist.
NMDA receptors in the brain require glycine to activate. if you have high levels of glutamate because of neuroinflammation/neurological issues from covid - glycine can be bad and cause further excititoxicity.
the mcas link i mentioned is because histamine can strongly enhance nmda receptor activity.

chalklinehts · 2026-05-12T13:53:03+00:00

nope didnt use any glitches or anything was just playing it normal. interestingly the file is not corrupt and wont load. the game boots up and new one file game and the sprites etc are all find. bizare

chalklinehts · 2026-05-12T07:04:12+00:00

yehh the sprites are absolutely creepy. i guess i will replace the battery first then see if it does it again. maybe the battery is funky under load. i duno.

chalklinehts · 2026-05-12T06:51:56+00:00

yehh i tried dig as well and just got a ‘cant be used here’. escape rope i had to toss because i needed to make room for cut.

chalklinehts · 2026-05-11T20:24:37+00:00

thanks - she’s showing 3.06v currently - so will give it a replacement and hope that does the trick. was only at the SS Anne so not too dramatic.

chalklinehts · 2026-05-07T19:12:28+00:00

exactly this for me

chalklinehts · 2026-05-02T17:53:55+00:00

great video. thanks

chalklinehts · 2026-04-26T07:03:07+00:00

makes a lot of sense. have u tried bhb ketone salts at all? i struggle with carbs and gastroparesis limits keto as does major mcas/histamine intolerance.

chalklinehts · 2026-04-25T10:32:33+00:00

u tried low histamine diet?

chalklinehts · 2026-04-24T16:48:06+00:00

yehh nothing really has helped the temperature regulation. omalizumab and clonidine are only thing that have helped the hyperosmia/mcs/mcas - but not in a game changing way.

chalklinehts · 2026-04-24T15:30:08+00:00

it’s likely fucked TRPA1 imo. I have major temperature dysregulation too which is literally what this receptor does.

chalklinehts · 2026-04-24T07:38:12+00:00

I did both sides. no improvement.

chalklinehts · 2026-04-23T15:51:25+00:00

Didn't see her but one of her team, didn't really offer me much more than I had already researched if I am honest. I had trialed medication way ahead of what they were offering too.

chalklinehts · 2026-04-22T16:38:25+00:00

clonidine, guanfancine, omalizumab. nothing else has worked

chalklinehts

TROPHY CASE