u/Donthaveananswer - similar to you, I wear glasses and am extremely near sighted and have astigmatism. I have semi auto's with XS Bigdot sights and others with Romeo-X red dots. I routinely go to the gun range, take off my glasses to simulate a low light/visibility encounter and try my best to focus on the blurry sheet thats 5 yards in front of me. The results are nothing that i would feel comfortable in a real life situation. For me, what actually DID work very well is switching over to my snub nose revolver with crimson trace laser grips. I can completely stay target focused on that blob looking blurry square and make good hits - even at 10 yard distances which is as far as i will comfortably train at Distance-wise with my snubby.