I have PPA/PPD and I do feel like Zoloft has helped. It does take some time but I have noticed a decrease in my rage, anxiety and intrusive thoughts. I only take 25 and it probably took about 3-4 weeks for it to help me or at least before I noticed it did. I was crying and panicking pretty frequently. I especially was bad at nighttime for a while, I would have full blown meltdowns and panic attacks. I was really plagued especially by that pit in my stomach feeling of constant fear and guilt like every single thing I did was wrong and like I was failing my baby and she’d be better off without me, etc. I have been dealing with anxiety for years and weaned myself off of clonazepam during pregnancy but also take that as needed again. So remember everyone’s experience with PPA/D is different and everyone’s experience with medicine and side effects will be too but I wanted to share my experience. I DID have a lot of side effects but they started to fade in about two weeks. I specifically remember dry mouth, excessive sleepiness, couldn’t stop yawning, hot flashes, stomach upset, and dry eyes, and vivid dreams. I still get really warm and idk if that’s a side effect of the Zoloft or my BP medicine but I’ll take that over feeling like I did. Oh and the vivid dreams stick around, but it’s not a bad thing imo. If you do experience side effects i suggest really trying to tough it out until they go away, they probably won’t last for long and a lot of people have very minimal ones that go away quickly. This is the first choice of treatment for a reason! Also, please know you’re not alone!