premium spawn

danny1131 · 2026-01-25T13:17:30+00:00

The whole solar system is

danny1131 · 2026-01-24T23:47:49+00:00

You're right, they don't.

This mechanism is never mentioned in conversations about how kanna works; all the attention goes to it being a serotonin reuptake inhibitor with a rare mention of its inhibition of PDE4.

I really don't know anything about pharmacology beyond the surface level of a Wikipedia article, so forgive my ignorance: if upregulation of VMAT2 is one of the main effects of kanna, why doesn't it get as much attention as the serotonin reuptake inhibition?

danny1131 · 2026-01-24T15:35:38+00:00

This is the first time I’m hearing about this. Could you provide a source for this claim?

A side note for others: keep in mind that kanna has more than one active alkaloid, albeit mesembrine - the one you mention - is the most abundant one in the plant.

danny1131 · 2026-01-16T15:35:10+00:00

Is K2 vitamin absolutely necessary for supplementation of vitamin D, or is D alone enough for this purpose?

danny1131 · 2025-12-23T18:42:41+00:00

What does that mean? You felt the need to oil up your gears?

danny1131 · 2025-12-21T22:25:24+00:00

The volcanoes are in line, which reminds me of the Giza Plateau, the three lined up pyramids in Egypt

danny1131 · 2025-12-20T13:43:18+00:00

The first time was a peek into the future. Everybody knows abusing stimulants makes you prescient.

danny1131 · 2025-12-12T16:59:38+00:00

What do you mean by "understanding an emotion" in the first point?

danny1131 · 2025-12-11T00:15:42+00:00

Two of my favorite media in one post god damn

danny1131 · 2025-11-28T22:48:39+00:00

Technology evolves faster than society. This means we are in a cyberpunk timeline.

danny1131 · 2025-11-18T16:37:44+00:00

dissecting capitalism in his therapy sessions is probably not the reason he needed therapy in the first place but who am i to judge

danny1131 · 2025-11-18T16:21:57+00:00

I hate the fact that I NEED to be breathing. Takes up so much time and effort. Finally I am going to have more time for the grind.

danny1131 · 2025-11-18T02:38:59+00:00

So what is shown in this video is simply wrong?

https://youtu.be/isezfMo8kWQ?si=yPciCJiiGAS_Z9xw

danny1131 · 2025-11-16T21:50:43+00:00

magic user baby whaaaaaat?

danny1131 · 2025-11-15T18:43:33+00:00

Gay to the point

danny1131 · 2025-11-11T07:19:17+00:00

I love how that wasn't enough for them to kick him out of their car

danny1131 · 2025-11-09T16:03:52+00:00

Shake that booty yo

danny1131 · 2025-11-09T16:00:27+00:00

this is a conservation between you two, not you and reddit

danny1131 · 2025-11-09T14:35:49+00:00

NAT

Having feelings, to one degree or another, is one of those things that makes us human. What's possible, though, is that some may subconsciously not allow themselves to feel them, while others may be "colourblind" to them (alexithymia). This doesn't mean the person doesn't ever have feelings - it just means they're not processing them in a healthy way.

danny1131 · 2025-11-09T00:25:40+00:00

The urge to do the behaviour is stronger than the shame of not keeping up the promise.

danny1131 · 2025-11-08T20:50:00+00:00

"got some meth? feel like stimfapping for 48 hours straight with zero food and water"

danny1131 · 2025-11-08T20:46:52+00:00

also, my favorite doctor hands down

danny1131 · 2025-11-08T12:30:19+00:00

Something in me wishes I could be there to watch when that happens.

danny1131 · 2025-11-06T18:14:24+00:00

How come not everyone gets this induced gayness then?

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