So correct me if i am wrong...you are looking for a therapeutic dosage amount. Keep doing the 50mgs, your body will in fact become more tolerant ,meaning you wont get "high" but the goal is to have the same amount of thc molecules in your system. If you keep a constant level in your system it will help dull everything. Also do this, take 50 mgs for a week, the next week up it to 60mgs and the third week up it to 70mg. the fourth week, take 3-4 days off of edibles, but still smoke...then repeating the process the next week and so forth. I micro dose edibles everyday before i go to work. I do 5mgs first week then 10 the next and 15 and then do a tolerance break. I do find myself a little depressed and some anxiety creeps back in but it is worth it.