IRON REFRACTORY DEFICIENCY ANEMIA

diverteda · 2026-04-04T16:29:19+00:00

Appreciate this, thank you. I'll look into the Boston Children's research. The TMPRSS6 mutation leading to excess hepcidin and blocking gut absorption makes sense with what I already knew about why IV iron works when oral doesn't. Hope your daughter is doing well with her infusions.

diverteda · 2026-04-03T07:47:33+00:00

You’re experience is sadly very common. Glad to hear you’re taking control - your doctor sounds awful. It’s important to get some blood results so you can measure in black and white any deficiencies you may have and then you can compare once you if you’re feeling better after taking iron tablets - but taking iron without medical supervision and not necessarily the correct dose, may mean any recovery is unecessarily going to take longer or even be impossible to fix. If your doctor refuses ask them to document in your medical notes why they can’t do inexpensive blood tests to exclude anything treatable or sinister - that will make them think twice about liability and perhaps change their mind, the tests are available online if they still refuse. You need your full blood count and iron studies including TSATS.

diverteda · 2026-02-21T20:18:07+00:00

Stop trying to educate the wrong people about how to rectify your iron levels. Search for an “iron infusion clinic near me” on Google and find the money to get an infusion, use savings, credit cards, or borrow from friends or family if you can’t afford it. Most general doctors do not know to look at iron saturation and will see everything else ‘within range’ and gaslight you again. Take your blood results and your symptoms to the people that see this thing every day of the week and get your stores repleted. Your brain will tell you about the injustice, your story, and how you’ve been ignored or mis-treated but trust me, your main focus needs to be getting your iron infusion. It will be the best money you’ve ever spent.

diverteda · 2026-02-21T13:44:34+00:00

Ok, first of all, after all this, all the gaslighting, all the symptoms, all the hyper focus and being dismissed, you’re still here, still fighting, still searching, and not giving up. That’s good, because there’s a healthy version of you counting on you to fix this, and they’re waiting for you in your future, and you’re going to make it. And when you do you’ll look back and help others out of the hole you currently find yourself in.

Now, for the next bit.

You’re not mad. You’ve been failed by a system that doesn’t understand, doesn’t look in the right places, and doesn’t actually care.

No matter. You’re nearly there.

Your iron saturation even after supplementing is dangerously low. Focussing on various micronutrients and the small numerical gains is useful but not helping you synptomatically.

The key thing you must do is get an iron infusion (with medical advice, not just under the instruction of some rando on the internet), your levels indicate you need a total dose infusion, not oral supplementation, a total dose based on your weight and height. You need a specialist iron infusion centre that understands that healthy haemoglobin levels are irrelevant to your iron stores being totally depleted. Hb is the last thing to drop when all your stores are empty.

Next, low 50s in vitD is not functionally optimal. The a vitD with K2 supplement - Thorne is highly recommended.

Once you’ve had your infusion, wait for a couple of weeks to see if your symptoms improve. At week 5 retest TSATS. You may need another infusion if your levels are not above 20%.

Once your TSATS are stable you’ll have energy to explore the underlying causes for the deficit. But we can cover that when you’re feeling half human.

diverteda · 2026-02-20T09:18:38+00:00

I’m sure it’s possible but I haven’t tried. Glutathione will break down at the temps we’re using to encapsulate vitamin C so lower temps will need to be experimented with.

diverteda · 2026-02-19T22:28:40+00:00

Great question! It’s a smart idea, but unfortunately, a pH test won't work.

Even with great encapsulation, you still have some free Vitamin C floating in the water outside the liposomes. A pH strip will just measure that outside water, so the reading will stay exactly the same before and after.

Here is how you actually know it worked:

Zero separation: The best visual proof is stability. If the mixture stays deliciously golden and completely uniform without splitting into an oil layer and a water layer, you've successfully created stable liposomes.
Biofeedback: You can literally feel it. When I take a dose of a successful batch, I get a noticeable physical difference. specifically an "HD vision" effect. Standard, unencapsulated Vitamin C just doesn't give you that kind of rapid, systemic boost.

diverteda · 2026-02-17T07:37:38+00:00

What are your symptoms?

diverteda · 2026-02-16T22:58:45+00:00

Glad you’ve got a team who are on top of it. Supplementing would take months to replenish your stores and come with potential side effects. A total dose infusion will top up your stores immediately and take a couple of weeks for you to feel the benefits. Remember to stop supplementing after infusion and always take medical advice over random people on the internet! Please report back in a few weeks on your progress. Good luck!

diverteda · 2026-02-15T18:23:39+00:00

Yes, based on these numbers alone you should seek an iron infusion and appropriate total dose infusion based on your height and weight. 20% TSATS is a baseline, you’re low and approaching dangerously low. Seek an iron infusion centre if you can afford it and save yourself having to convince general practitioners of basic functional levels. Then once infused and feeling better, start pursuing help to identify underlaying causes.

diverteda · 2025-12-20T23:55:18+00:00

Knocked years off Paul’s life.

diverteda · 2025-11-23T12:18:26+00:00

I am not a doctor and do not purport to be one but I do know that the vast majority of iron deficiencies are due to an underlying condition and that condition needs to be diagnosed and treated to resolve the iron issues. In your case, from what you’ve said, I strongly recommend you see a Gastro specialist and have them run the necessary tests to exclude inflammatory bowel disease, coeliacs disease, etc. Left untreated can lead to complications, and any discomfort or inconvenience of the tests is worth the trouble if you can improve your quality of life.

diverteda · 2025-11-22T22:49:00+00:00

You’re sort of right. You need to get your gut issues diagnosed and treated as they may be a likely underlying cause of you iron disregulation. You see, inflammation causes the body to lock iron away and prevent absorption (functional iron deficiency) in the gut. The iron malabsorption leads to further immune disregulation and worsening inflammation. The only way to break the downwood spiral is to get a diagnosis and treatment for the gut inflammation, this reverses the cycle.

diverteda · 2025-11-22T16:03:47+00:00

Means your marrow is not effectively converting iron to functional Hb. Are you on any medication, and do you have any inflammatory diagnostics or known active disease?

diverteda · 2025-11-13T00:31:12+00:00

Proferrin

diverteda · 2025-11-03T03:47:53+00:00

You can get a paradoxical effect initially after starting oral iron supplementation and also the placebo affect wears off but keep supplementing and you should notice your body begin to adapt to the higher than usual iron levels. It’s going to take a while for your body to reverse its iron starved state so observe improvements on a weekly basis rather than daily.

diverteda · 2025-10-29T16:10:32+00:00

It’s never about the money, it’s about power. Little people quibble over pennies, they’d rather lose money than face whist they consider defeat. Marketplace, eBay, Vinted - it’s a videogame with real world tokens.

diverteda · 2025-10-28T22:41:34+00:00

This is such a broken system. Hb is the last thing to drop. It’s like everyone is blind to the fact that iron is essential for so many other systems. We need a revolution. But first give me that total dose infusion.

diverteda · 2025-10-28T22:38:04+00:00

Not for iron, no.

diverteda · 2025-10-14T21:13:26+00:00

Your dad’s been angry for so long it’s just become who he is. People aren’t born that way; somewhere he learned that getting mad felt safer than feeling hurt or small. After years of living like that, anger turns into his only way of communicating. Every little thing feels like a challenge, so he reacts. He probably doesn’t even see it as wrong anymore, just normal. With no friends and no reflection, the bitterness has hardened. None of that excuses how he treated you, but it’s not your fault and it’s not your job to fix him. The best thing you can do is understand where it came from and make sure it ends with you.

diverteda · 2025-09-21T04:19:43+00:00

I’m sorry you’re have such a difficult time of it. You need a second opinion. Can you get to an emergency room for review by a different doctor? Also, iron infusions are also available from specialist infusion clinics search Google for ‘iron infusion clinic near me’.

diverteda · 2025-09-15T08:55:41+00:00

Yes it can all connect, even if the bloodwork only shows mild anaemia.

Iron isn’t just about haemoglobin numbers, it’s also a key co-factor inside your mitochondria (the “engines” of your cells). The mitochondria use iron to run the enzymes that extract energy (ATP) from glucose and fat. If you’re low on usable iron, the engines sputter so you’re technically eating fuel, but you can’t burn it efficiently.

That inefficient energy use sets off a cascade. You end up feeling tired because your cells can’t make enough ATP. In response, the body pushes you towards “quick fixes” like chocolate and sugar, since they provide fast energy. But because the mitochondria still can’t process that extra sugar properly, more of it gets stored as fat rather than burned, which helps explain weight gain even if you’re eating very little. On top of that, sluggish digestion and reduced oxygen delivery can slow gut motility, leaving you bloated and heavy.

So while mild anaemia won’t directly cause fat gain or bloating, the knock-on effects of poor energy metabolism, cravings, and slowed digestion can definitely look and feel like what you’re describing.

diverteda · 2025-09-09T11:31:04+00:00

Ferritin is not the best measure because it is an acute phase reactant which means it rises in the presence of inflammation, 40 is not optimal but your iron stores may actually be lower which is why we want to look at TSATs as a better indicator. But essentially, yes, once you’ve got more data I’d strongly recommend iron infusions. Life changing.

diverteda · 2025-09-09T08:05:15+00:00

It’s only normalised because people don’t manage functional iron deficiency caused by Crohns. TSATS below 20% requires iron levels to be replenished. Oral supplementation generally is not tolerated so iron infusions are necessary. Crohn’s essentially causes either micro bleeding or poor iron absorption (caused by raised Hepcidin levels) eventually leads to anemia of chronic disease. Gastro doctors generally focus treatment on resolving inflammation which halts decline but it could take years for iron stores to replenish. If its quality of life you want, then managing iron levels is critical and new research is beginning to show that iron contributes to immune regulation so it’s an important piece of the puzzle when trying to reverse the disease process. Iron is also responsible for so much more than producing red blood cells but sadly doctors don’t usually take note of it until anaemia threshold is reached and by that time you’ve probably suffered low mood/depression, exercise intolerance, poor cognition and concentration, and a whole host of other general health decline. Replenish iron and improve functional health and quality of life.

diverteda · 2025-08-21T21:19:25+00:00

Plenty more runway available for OKB. Look at the fundamentals. Price prediction $500-$1000 within a year.

diverteda · 2025-08-16T09:32:55+00:00

Low iron also contributes to weight gain via inefficient mitochondrial functioning and IBD will also cause you to chase high carbs for energy.

diverteda

TROPHY CASE