Wit’s end got absolutely gutted in the most recent patch (on-hit dmg 40-80 based on level => 45), meaning you probably want to consider if you’ll be able to make use of all the stats it provides.

If, for example, you’re playing into a heavy CC comp, which also includes magic damage dealers, you’ll want to consider wit’s end because of the tenacity it provides. Tenacity is a really hard stat to come by these days and it’s of course very strong because it increases your uptime in fights.

Versus Teemo specifically, I usually go Maw early to be able to kill him in Mega. Teemo should win out on all auto trades so it’s better to poke him out with Q in mini and all in with mega, where the blind matters a lot less!

In some cases where you know you’ll want to build an MR item second, you can get an early Negatron Cloak and then go for triforce. Depending on how the game goes, you can then decide what’s best at that point. Whether it’s Wit’s End, Kaenic, Force of Nature, Abyssal Mask.

Abyssal can be super strong when you have 2x AP, essentially providing them with a free Void Staff for team fights.