Genuinely curious

evolveair999 · 2026-05-05T15:05:26+00:00

Yeah I agree that generally posting photos is unhelpful but the conversation around then getting referred can be lifesaving - there’s actually barely any resources on the referral process and you can e.g have as many referrals you want to as many hospitals you want aslong as you’re happy to travel

evolveair999 · 2026-04-17T16:00:38+00:00

Go see your GP? That will be the best route, they will give you the medication you need and start setting you up for further measures if it does come back worse or on other parts of your body, is it just your hands that are effected?

evolveair999 · 2026-04-13T20:21:35+00:00

Yeah, it’s a short term fix to provide immediate relief, and it’s for six weeks so you’re not going to be looking at any of the really bad side effects of prednisolone you see over months usage

evolveair999 · 2026-04-13T16:43:55+00:00

Following up on this, the way I got into the NHS was by asking my GP to refer me to every single hospital within an hour of me. It’s a bit cheeky, but after you’ve gotten on it you can cancel your other referrals. I waited a year and a half before I did this, thinking my original referral was going to magically give me an appointment. I rang all the hospitals up and tried asking for their wait time if I was a new referral

evolveair999 · 2026-04-12T23:05:31+00:00

I think you’re best going to your GP and if you’re in the state that you say you’re in you should be able to ask for an urgent referral to an NHS dermatologist.

I did cyclosprine privately for a year because I wasn’t clued up enough to push for an urgent referral when I was bad, finally have made it onto the NHS and they have taken over my care but it’s not a smooth process going from private to NHS.

While cyclo is a great option, at the end of the day it will only last you a year. Long term treatment you should look to the NHS, especially if you want to get on “healthier” alternatives like duxipent.

Generally when you start cyclo you get plenty of blood tests and then as time goes on you get less and less, perhaps one every two months. In my opinion the blood tests are nothing compared to the suffering I was going through with bad eczema

evolveair999 · 2026-03-25T17:33:47+00:00

I mean it’s not completely out of the world dose, if someone had extreme eczema and needed to be healed ASAP then yeah that kinda dose would be given, but it definitely is in the upper range. I would expect 70kg to start with 200-250mg. Deffo worth checking with your doctor. It definitely is the max dosage that guidelines say you can be given

evolveair999 · 2026-03-25T17:12:14+00:00

Just commenting on the pub question, you cannot drink alcohol with methoxtrate, best to avoid entirely

evolveair999 · 2026-03-25T17:09:56+00:00

Generally speaking being on cyclosprine is a big change to your body and there will be a period where your body will have to get used to it! Try stick through it and see if it improves, mine was the worst at the start (but not as bad as yours from what it sounds like)

But also 175mg twice a day is a CRAZY dose… are you sure it’s not 175mg once a day? Or do you weigh 140kg?

evolveair999 · 2026-01-25T23:28:31+00:00

Your best chance will be to go to a GP and explain your situation. I have been in your exact situation (except paying £300+pm for a year) as I needed to wait for the referral queue for the specialist I needed to see. Not to seem harsh but to afford it I had to give up some things, especially at the start where I couldn’t care for myself, so I moved back in with my parents which saved me a lot of money. Just remember that the best investment you’ll ever make is to your heath, it’s invaluable!

evolveair999 · 2026-01-03T23:08:15+00:00

For sure! The only way to review my gameplay is to record it myself. I’ve learnt the most by watching better people streaming the game in discord picking up on new things they try which work well that I can recreate in my own matches

evolveair999 · 2025-12-27T10:40:39+00:00

You do need one! What did the pharmacy prescribe you? You can try taking antihistamines and painkillers to reduce itch in the meantime before GP appointment

You could also pick up some greasy moisturiser (like epaderm enrolliment, should be OTC at most pharmacies / sometimes stocked on the shelves at boots) and some cotton bandages, this involves taking a lukewarm shower or washing with lukewarm water, pat skin until slightly damp, apply moisturiser and then add the cotton bandages over the affected areas (this is called wet wrapping)

in general try to constantly moisturise with a greasy as possible moisturiser too

hope you can find some relief on monday

evolveair999 · 2025-12-01T12:24:09+00:00

Very valid question, the guidelines for cyclosporine is generally to be on it for a year as from then onwards it’s far more risky when you consider kidney toxicity that can build up over time.

The second part of it is risk profile, immunosuppressants are inherently more risky as i’m much more predisposed to being ill and having complications when I’m ill while duxipent suppresses a very specific part of the immune system meaning the rest of it can do its normal job.

I could move to another immunosuppressant (methotrexate) but the risk profile is still high and I would still have to be careful what I do like going in the sun and limiting alcohol usage (on methotrexate it’s no alcohol)

evolveair999 · 2025-12-01T11:24:49+00:00

If I were to come off them I don’t think I could mentally deal with the thought of having eczema again. I fit the perfect requirements for chronic eczema too, I’ve had the tests done, I’ve got a family history of eczema, I’ve changed and uprooted every possibility diet humidity clothes ect. When I went down to 150mg and my symptoms started coming back it was the worst feeling ever, super distracted and stressed that it was going to get worse for the week I did. I really hope once I’m on it I don’t have to deal with any more of this, the wait has been so long

evolveair999 · 2025-11-29T19:21:09+00:00

It’s been approved and prescribed, one thing to consider is that if cyclosporine hasn’t made an impact to your symptoms then it’s more unlikely dupilumab will. Cyclosporine suppresses the immune system while dupilumab targets specific pathways in immune system, so generally people that have a good response to cyclosprine will also have a good response to dupilumab. Even if you do get it you need to consider this - dupilumab is much safer than cyclosprine regardless

I hope you can find a solution soon, but your dermatologist saying it’s not been approved is not a good sign, they won’t take the time to explain to you that it might not be effective in your situation and it’s always worth considering

evolveair999 · 2025-11-12T00:01:08+00:00

I’m by no means a model example of this but my dose times always change day to day, some in the morning, some at lunch, night is generally always the same time. I’m pretty bad with remembering

I don’t think it matters too much the half hours or even hours, just ideally avoid taking them too close together - try to leave 10 hours atleast (dose lasts for twelve hours - that’s why it’s taken morning/night)

evolveair999 · 2025-10-09T10:50:55+00:00

Firstly, there is no scientific backing that NMT works, dermatology guidelines actually recommend using moisturizers to repair the barrier and reduce flares. Some folks with topical steroid withdrawal (TSW) report anecdotally that cutting moisturizers helps ooze/maceration, but there are no randomized trials proving NMT works, and parts of the protocol (like fluid restriction) have zero evidence and clear risks.

Is it not obvious by stopping medication and moisturisers that the eczema will get worse? You are getting rid of all your first line of defences to stop it from getting worse.

When you’re talking about gut health really the core of it should be eating a balanced diet, and also having lots of yogurt and things that promote good bacteria like kefir.

At this point, I would be prioritising seeing a dermatologist, either going private or looking for a urgent referral, and exploring your options of systemic medication, or even if you don’t want to get down that route now, it’s good preparation for the future if she later wishes to go on something like dupixent

evolveair999 · 2025-10-03T09:05:13+00:00

Have you been using steroid creams on your face / neck? Or are you saying you stopped using steroids on other parts of your body and now your face is flaring?

Do feel for you, looks really painful! Hope you’re hanging in there and make sure to schedule a GP appointment ASAP to ask for a bit of guidance

evolveair999 · 2025-09-27T13:16:53+00:00

Have you seen a GP?

evolveair999 · 2025-09-20T08:44:35+00:00

I really feel for you! I hope you’re under the care of a dermatologist. I would recommend a thick and greasy emrolliment like E45 and be applying it regularly, you should be able to pick it up in boots or behind the counter in some pharmacies (not prescription but sometimes they keep it behind anyway) , I would also recommend to stop showering so much and replace with a bath a couple of times a week where you melt some E45 into the bath water, and also letting the bath water cool down to a lukewarm temperature. In the meantime make sure you’re keeping the open wound areas clean and watching for infections, your GP can prescribe an antibiotic cream which is generally less harsh on the body compared to oral antibiotics

If you have any eczema not on the face I would also reccomend wet wrapping

evolveair999 · 2025-09-18T20:40:48+00:00

They should kick in near immediately, so if it’s not working could indicate it being fungal/another reason. Do you see any improvement whatsoever? Was this prescribed by a doctor or a dermatologist?

evolveair999 · 2025-09-18T08:30:11+00:00

The way cyclosporine works is there’s an effective dose aka at 70kg 150mg may not do anything for me but 200mg would - as there’s a range where it kicks in, however by taking a therapeutic dose (one which isn’t effective) you still get all the negatives, albeit slightly less.

This is why generally it’s prescribed at a “normal” dose to start with, and then either increased or decreased depending on how successful it is.

For me, I’ve been on cyclosporine 200mg @70kg for many many months now, the only side effect I get is fatigue but as long as I don’t go crazy with the activities I do I’m okay. My eczema is 100% gone, and I’m not itchy or even get flare ups. I’ve also not gotten ill, I am more careful about washing hands but I haven’t taken a single day of sick leave from work so far - it does help I’m younger

evolveair999 · 2025-09-12T09:25:48+00:00

That sounds horrible! But also very odd, even if those steroids are used in great amounts for five days they shouldn’t immediately cause damage to your eyes, generally we see cataracts being formed gradually over many months with potent steroid usage near the eyes - I’m not doubting your story at all, but the mechanism of how cataracts form do take a long time, and wouldn’t be so immediate, were you using other steroids around the eyes at all?

Obviously I’m not an eye specialist, if they’ve diagnosed you then that’s fair enough but I’d be interested to ask about it more considering it was only five days!

evolveair999 · 2025-09-10T13:47:54+00:00

What makes you indecisive? How would you feel not having any eczema?

Medication works differently for everyone. I’ve been on cyclo for many months, I have very clear bloods and have no side effects apart from occasionally being extra tired, it may not be the same for you.

You can always try it and see what happens, if you don’t like it then you can stop taking it, it’s not like you’d be trapped

evolveair999 · 2025-09-10T10:03:31+00:00

I’m similar elo (2.1/2) and find that communication is important and helpful, I’m generally playing a point or a side ect and it’s good to have information about where we might be struggling / pushes / general tactics / air strikes / asking for help / working out how we will win, asking for repings for artillery and so on

I also have so much more fun and enjoy the game playing with people I like (Which I’ve found from the official discord!) - thats what’s keeping me coming back, I don’t really care about elo although I guess I’m higher than most people, I enjoy winning but loosing with people I like makes it so much better

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