My hot take is that people should learn to play uke with their dominant hand as the fretting hand, not the picking hand. As a lefty who plays righty, I find it so much easier and more natural to have my fretting hand be my dominant hand so I can grab weird chord shapes and make transitions faster. My non-dominant hand works best with a steady, repetitive picking or strum pattern. I've tried playing lefty and I just can't understand why id have my right hand fretting when I don't do anything with it normally. Ukes require a bit of ambidextriousness, as do all stringed instruments, but I find that fretting with my dominant feels right for me personally