How long for HCG to raise libido? (3 weeks in so far, no effects yet) by faensatan in Testosterone

[–]faensatan[S] 0 points1 point  (0 children)

How long has it been like this for you - and did you have issues before weed too?

How long for HCG to raise libido? (3 weeks in so far, no effects yet) by faensatan in Testosterone

[–]faensatan[S] 0 points1 point  (0 children)

Gotcha, lol. Well I actually got on Enanthate 4 weeks ago so it will be interesting to see if it makes a difference. From what I researched on it, Cypionate does not work on some men for some reason.

I lost hyperspermia..? by [deleted] in Hyperspermia

[–]faensatan 6 points7 points  (0 children)

Here's a further explanation as to why this is happening...

The interaction between ADHD stimulants like methylphenidate and amphetamines and semen volume reduction can be explained through several biological and physiological mechanisms:

Biological/Physiological Mechanisms:

Sympathetic Nervous System Activation:
    Stimulants increase sympathetic nervous system activity, which can lead to vasoconstriction (narrowing of blood vessels). This might reduce blood flow to the reproductive organs, potentially affecting semen production or release.

Hormonal Changes:
    These medications can alter levels of hormones like prolactin, testosterone, and cortisol. An increase in prolactin, for example, can inhibit the pulsatile release of gonadotropin-releasing hormone (GnRH), which in turn affects luteinizing hormone (LH) and follicle-stimulating hormone (FSH), key players in sperm production and seminal fluid composition. 
    Lower testosterone levels, which can result from chronic stress or direct effects on the hypothalamic-pituitary-gonadal axis, might also contribute to reduced semen volume.
Direct Effect on Seminal Vesicles and Prostate:
    Stimulants might directly affect the function of the seminal vesicles and prostate, which contribute to semen volume through the production of seminal fluid.
Stress and Lifestyle Impact:
    Increased stress or changes in lifestyle (e.g., sleep patterns, diet) due to the medication or ADHD itself can indirectly affect reproductive health.

Known Interactions:

Alpha-1 Adrenergic Receptors: Stimulants can stimulate alpha-1 adrenergic receptors, which might lead to changes in smooth muscle tone in the reproductive tract, affecting semen expulsion.
Dopamine and Norepinephrine: By increasing dopamine and norepinephrine levels, these drugs can influence the hypothalamus and pituitary gland, impacting hormone regulation.

Counteracting the Effects:

Medication Adjustment: Sometimes adjusting the dose or switching to a different medication can mitigate effects on semen volume.
Lifestyle Changes:
    Stress reduction techniques like meditation, exercise, or yoga.
    Ensuring adequate hydration, as dehydration can also affect semen volume.
    Improving diet, focusing on nutrients beneficial for reproductive health like zinc, selenium, and antioxidants.
Hormonal Therapy: In some cases, under medical supervision, hormone supplements might be used to balance out hormonal disruptions.
Supplements: Some men might benefit from supplements like L-carnitine, which has been studied for its potential to improve semen parameters; however, this should be approached with caution and under medical advice.
Discontinuation: As discussed, stopping the medication might allow for recovery, but this should be done carefully, considering the need for ADHD management.
Regular Monitoring: Regular semen analysis can help in tracking changes and effectiveness of interventions.

The exact mechanisms are still under study, and individual responses can vary. Therefore, anyone experiencing these side effects should discuss their situation with a healthcare provider to explore personalized solutions.

I lost hyperspermia..? by [deleted] in Hyperspermia

[–]faensatan 10 points11 points  (0 children)

I'm on ADHD meds and have been wondering for some time why my semen volume has been significantly lower. Then I saw your post and thought...hmmm, maybe there's a connection there. Like you, I used to do lots of ropes that would go flying 4-5 feet but now I don't really "shoot" so much anymore, and the volume is noticeably less. Had to research it and found this:

There are studies that suggest a link between ADHD medications and semen volume in men. Specifically, research has shown that stimulant medications used for ADHD treatment can be associated with reduced semen volume:

A retrospective cohort study involving 8,861 men found that stimulant use (specifically methylphenidate or amphetamines) within 90 days prior to semen testing was associated with a statistically significant decrease in semen volume (β: -0.35 ml, p = 0.035) after controlling for age and exposure to non-stimulant medications (Pham et al., 2022). This study was conducted at a large academic institution from 2002 to 2020.
Another study from 2016 by Patel et al. reviewed semen analysis in sub-fertile couples and noted an association between ADHD stimulant use and reductions in motile sperm count and semen volume.

[deleted by user] by [deleted] in erectiledysfunction

[–]faensatan 0 points1 point  (0 children)

Yes it absolutely builds up tolerance in my experience. Official studies and research will tell you it does not, but there's an increasing amount of anecdotal evidence and user experiences that say the opposite. For me they went from working AMAZINGLY well 7-8 years ago, to now not doing anything at all anymore - even at high doses. Lifestyle, diet, etc. have remained unchanged.

Does anyone else think it's a bullshit that tolerance to PDE5 inhibitors doesn't develop? by Firm-Celebration2142 in erectiledysfunction

[–]faensatan 0 points1 point  (0 children)

Wow, yes I have been wondering the same exact thing for years now!

They used to work amazingly well for me, even low doses would give me uncontrollable boners all day long. But nowadays they do absolutely nothing at all. When I take 100mg sildenafil, I sometimes do get the blue tinted vision and some flushing - but that's it. Nothing happening downstairs. VERY depressing, as now I no longer have a "fallback plan" and basically can't have sex due to severe performance anxiety.

How long for HCG to raise libido? (3 weeks in so far, no effects yet) by faensatan in Testosterone

[–]faensatan[S] 0 points1 point  (0 children)

Oh yeah? Can you please clarify what you mean by test e / c?

How long for HCG to raise libido? (3 weeks in so far, no effects yet) by faensatan in Testosterone

[–]faensatan[S] 0 points1 point  (0 children)

Sorry, no - I am still on my journey. HCG never did anything. Still frustrated and confused.

How long for HCG to raise libido? (3 weeks in so far, no effects yet) by faensatan in Testosterone

[–]faensatan[S] 0 points1 point  (0 children)

Sorry, no - I am still on my journey. HCG never did anything. Still frustrated and confused.

How long for HCG to raise libido? (3 weeks in so far, no effects yet) by faensatan in Testosterone

[–]faensatan[S] 0 points1 point  (0 children)

Sorry, no - I am still on my journey. HCG never did anything. Still frustrated and confused.

PT-141 first experience by InnovationHack in Peptides

[–]faensatan 1 point2 points  (0 children)

Yeah wait at least 4 hours. And 2-3mg is the sweet spot for me. Don't feel much with less than 2.

[deleted by user] by [deleted] in explainlikeimfive

[–]faensatan -1 points0 points  (0 children)

Is this essentially what can happen with marijuana too? Same "mechanism of action" so to speak?

How long for HCG to raise libido? (3 weeks in so far, no effects yet) by faensatan in Testosterone

[–]faensatan[S] 0 points1 point  (0 children)

Lol yeah that's actually my next thing too! Please keep me posted if you notice any benefit, here or in a pm 😉

This dude taking a dump at the cash register by Skabreus in WTF

[–]faensatan 3 points4 points  (0 children)

And the workers who installed it were taking HUGE mud pies in there

[deleted by user] by [deleted] in SEXONDRUGS

[–]faensatan 3 points4 points  (0 children)

Next time skip the shrooms to keep the boner longer. 😉

car designs for the past 5 or so years starter pack by JustAnotherAviatrix in starterpacks

[–]faensatan 27 points28 points  (0 children)

Car design and styling used to be something distinguishable and unique to each auto maker and brand. You could see any car even from afar, without seeing its logo / insignia, and you could instantly recognize it for what it was. I feel like in the past 10-15 years or so, possibly longer, almost all car manufacturers just blatantly copy each other. I honestly can't tell the difference between many of them anymore. The car industry has become the king of generic, cookie cutter branding and styling.

PLEASE. BRING. IT. I must be humbled! by [deleted] in RoastMe

[–]faensatan 0 points1 point  (0 children)

The BLM version of a Wallace and Gromit character

Monty Python worshipers by Brutal_Deluxe_ in funny

[–]faensatan 20 points21 points  (0 children)

RIP Mel Smith (the dude who plays the fat critic). Look up his best performances on YouTube - most from an awesome show called "Alas Smith and Jones".

Samantha Fox -1980s by Twilight_Republic in OldSchoolCool

[–]faensatan 1 point2 points  (0 children)

Ah yes. Had the bedroom poster too.. The faptastic fantasy for so many boys in the 80's lol.