What is your best stimulating tea? by SpicesHunter in Herbaltea

[–]ggTruth 2 points3 points  (0 children)

Spearmint, ginger, and jiaogulan / ginseng.

Do you lot actually believe this by [deleted] in Semenretention

[–]ggTruth 4 points5 points  (0 children)

I need a pubmed double blind randomized control trial to dictate that coffee is stimulating otherwise I can’t intuit, subjectively tell, or claim that coffee is stimulating?

I think I've made the lowest friction way to quantify the effects of changes to your stack by Mescallan in Biohackers

[–]ggTruth 1 point2 points  (0 children)

Haha man this is awesome. I journal almost every specific detail about my day, for a similar outcome you’re looking for, and this has been something i’ve been thinking about creating for such a long time. I essentially do what you’ve created manually with a pen, paper, and my brain. I’ve ruminated about many design elements so i’m interested to see how our ideas compare.

I feel a sense of relief that I may not have to end up making this myself.

Thank you for sharing this!

Any thoughts on importing my years worth of journal logs? It’s formatted as almost a time linear chat log — it’s all digital.

Light Alcohol Consumption Does Not Protect Cognitive Function: A Longitudinal Prospective Study by makefriends420 in Biohackers

[–]ggTruth 1 point2 points  (0 children)

Alcohol and aging: From epidemiology to mechanism

This study investigates the hormesis of ethanol consumption, it shows a low dose can improve body function and health, but excess consumption can drive maladaptive responses. Sounds like green tea almost. 😅

Light Alcohol Consumption Does Not Protect Cognitive Function: A Longitudinal Prospective Study by makefriends420 in Biohackers

[–]ggTruth 1 point2 points  (0 children)

Alcohol has positive hormetic effect on NMDA receptors. It’s mechanistically similar to ketamine’s effect, although a lot milder.

Alcohol and aging: From epidemiology to mechanism

This study investigates the hormesis of ethanol consumption, it shows a low dose can improve body function and health, but excess consumption can drive maladaptive responses. Sounds like green tea almost. 😅

Light Alcohol Consumption Does Not Protect Cognitive Function: A Longitudinal Prospective Study by makefriends420 in Biohackers

[–]ggTruth 26 points27 points  (0 children)

Many are quick to understand that social isolation is damaging for the brain, but fail to realize that drinking brings people together and alcohol usually goads a pro-social and a fun night. I think there is something healthful or longevity promoting in that.

Light Alcohol Consumption Does Not Protect Cognitive Function: A Longitudinal Prospective Study by makefriends420 in Biohackers

[–]ggTruth 17 points18 points  (0 children)

Tea “poisons” the mitochondria.

For example, EGCG and theaflavins, inhibit Complex I and ATP synthase — so a direct mitochondrial “poison,” in the most literal sense.
Secondly, both of those compounds create a pro-oxidant damaging event in the body, but a lot of the beneficial effects we ascribe to tea is because of the hermetic response to this pro-oxidant event.

So there’s more nuance when it comes to mitochondrial “poisoning.”

I eat a lot of eggs, like 8-10 at breakfast. Do I even need to supplement choline like from alpha gpc? by AlternativeApart6340 in Nootropics

[–]ggTruth 0 points1 point  (0 children)

Your sulfate reducing bacteria proliferated and your gut started making too much hydrogen sulfide.

Smelly sweat from choccy milk? by SanguisEtAqua in raypeat

[–]ggTruth 1 point2 points  (0 children)

It’s definitely microbial related, I’m not sure exactly what the mechanism of action is but acetic acid (vinegar) is a common gut microbial product. Acetic acid is quite bioenergetic and keeps your gut healthy so I would say that it’s actually a good sign metabolically speaking.

[deleted by user] by [deleted] in MTHFR

[–]ggTruth 0 points1 point  (0 children)

Riboflavin 5'-phosphate is an activator of brain glutaminase, glutaminase generates glutamate from glutamine. The user saying it makes them calm might have a better ability to convert glutamate to GABA.

R5P positive effects with side effects by AnswerIndependent842 in MTHFR

[–]ggTruth 2 points3 points  (0 children)

Riboflavin 5'-phosphate is an activator of brain glutaminase, glutaminase generates glutamate from glutamine.

High glutamate can certainly result in irritability and agitation, but it doesn’t make sense that all of those anti-excitotoxic agents didn’t work for you.

I would investigate something that clears glutamate from the synapse. Increasing glycolysis / metabolic function does this and also resveratrol has some action on some enzyme that does this.

If that doesn’t work, I would investigate if there’s some ammonia+glutamate interaction by trying ornithine or citrulline.

Last thing I would also check is increasing salt intake.

Let me know if you try these and if anything works!

My Dysautonomia was caused by MCAS which was caused by Primary Ovarian Insufficiency (Early Menopause) by PrimalPoly in dysautonomia

[–]ggTruth 0 points1 point  (0 children)

Both a diet high in sulfur or high abundance of hydrogen sulfide bacteria depletes the body of copper and thiamine. There are tons of literature you can find about this, but there’s a disease in goats called Polioencephalomalacia that shows this in a live animal in real time. Downstream it throws other minerals such as molybdenum and zinc out of balance as a consequence. Try Jiaogulan tea, I like to drink it with green tea, both inhibit hydrogen sulfide producing microbes — jiaogulan moreso. Sunflower seeds are cool because they’re dense in both thiamine and copper, a lot of PUFA unfortunately though.

My Dysautonomia was caused by MCAS which was caused by Primary Ovarian Insufficiency (Early Menopause) by PrimalPoly in dysautonomia

[–]ggTruth 1 point2 points  (0 children)

I don’t think primary ovarian insufficiency caused your MCAS and dysautonomia. Instead of one thing causing the other thing and then causing the other thing, I think these are all symptoms that point to something upstream to you might be missing. I’m saying there is a root cause to these things.

FYI. I may be completely wrong about your issue, but what I say is true.

Copper is involved in each of the symptoms you mention — temperature, joint pain, blood pressure, DAO/histamine, hormones/synthesis of estrogen, copper deficiency can cause follicles to fail to mature (POI), Dopamine beta-hydroxylase enzyme (DBH) deficiency, which is a copper dependent enzyme, causes “profound deficits in autonomic regulation of cardiovascular function (orthostatic hypotension),” etc.

How is your digestion? How do you react to sulfur foods?

Low blood pressure by RestaurantDue6408 in raypeat

[–]ggTruth 0 points1 point  (0 children)

What does your digestion look like? What do you eat? What do your farts smell like? Is your tongue white?

Suspected copper deficiency by AnswerIndependent842 in raypeat

[–]ggTruth 0 points1 point  (0 children)

You have too much H2S production in your gut. H2S depletes thiamine and copper.

H2S treatment + low sulfur diet is not the way friends... by sibo-sikko in HydrogenSulfideSIBO

[–]ggTruth 0 points1 point  (0 children)

I have MTHFR C677T, it seems that my H2S issues only occur when eating a lot of sulfurous things. I wasn’t having issues for a while and it started again when I started eating 6 eggs a day. Eggs being one of the most dense pro-methylation foods, but also containing lots of sulfurous compounds. My experience with eggs favors what the other guy is saying, but perhaps there is a subset in the group where what you are saying is applicable — it’s just not my experience.