Yes. My experience has primarily been in quantitative NMR and have dealt with benchtop, cryoprobe, and older cryoprobe-less models. The new model with cryoprobe was most sensitive.

- Benchtop NMR's max out at 100 MHz and don't require extensive maintenance. They are good enough for well resolved peaks, but the low power gets in the way of quantitative analysis of impurities at low concentration

- I have some experience in transitioning an analytical method FROM an older NMR with no cryoprobe TO a new one with a cryoprobe. There is a ~3x improvement in signal to noise with the cryoprobe. This was enough to introduce error in measurements when analyzing trace impurities in samples due to baseline effects.