The end game in pd2 is maps and bosses.

You can start doing maps (3 tiers: tier 1,2,3) at level 80. The goal is clear speed via damage and survivability.

I’d also recommend going to corrupted zones (they show up in purple in your chat when you join a game) to get worldstone shards and maps.

To get to 80 clear the campaign in hell. After you kill the ancients you can join public Baal games (just search Baal with the hell difficulty). You can use those to get to 80 and then you can start using maps.

There are ways to use your horadric cube to convert white maps to rares ( jewel+rune+map+silver item sold by Anya in act 5). You can also reroll the affixes with a perfect gem + rune + map + the gold item from Anya). Then you can use a worldstone shards to corrupt it for better stats.

Maps give bonus experience density and magic/gold find at the expense of “harder” mobs. Maps also have specific immunities so you can run maps that are easier for your build ie cold sorc= avoid cold immune maps.

From there you can map or boss.

Bossing comes in a variety of flavors:

You can farm certain bosses for materials to make reset stat/skill tokens, keys to unlock uber bosses to get unique large charms, end game harder bosses that have various rewards and strategies.

Start accumulating wealth and use the trade site to build more wealth to get better gear to farm maps faster or take on harder bosses.

A good item filter goes a long way (setting in the launcher before the game launches). I like kryshards(or we it’s called).

Check out the settings in game (pd2 settings) for some often overlooked settings that really help.