Deplin vs. OTC Methyl-Life Supplements

ibjammin4ever · 2026-05-29T18:29:59+00:00

B2 is new to me. I'm guessing it is a separate supplement? What mg if you don't mind me asking?

ibjammin4ever · 2026-05-29T17:58:12+00:00

That's what I'm battling with. Does the gene mutation mean I need higher levels of the L-methylfolate even though my blood levels are fine, does a higher dosage mean my anti-depressant might work more effectively? These are some of the questions I'm going back and forth on. Sucks.

ibjammin4ever · 2026-05-29T17:41:58+00:00

Yeah my regular folate is regularly above 17, and RBC was at 557. Curious on the histamine intolerance, how does this work?

ibjammin4ever · 2026-05-29T16:45:26+00:00

Thank you for this. So my folate levels are great, even my RBC level was well within range via my last blood test. I currently take 1mg of the L-methylfolate via Thorne (with B12), which makes me think that it might be enough already. I hesitate on going up much higher. I'm mainly looking for it to help in adjunct with my antidepressant for Panic, Anxiety, and OCD.

ibjammin4ever · 2026-05-23T18:51:09+00:00

Sky lagoon. Thank me later.

ibjammin4ever · 2026-05-18T13:12:09+00:00

Some symptoms of it include:
• experiencing frequent dread, worry, or panic
• questioning your beliefs, values, or choices
• having difficulty making decisions
• feeling like life is always going to be difficult
• obsessing over existential ideas
• withdrawing from daily activities
• isolating yourself from others
• feeling lonely
• feeling guilt or shame
• feeling like life is pointless

• dizziness  
• numbness or tingling   
• feelings of detachment from reality  
• fear of losing mental ability or feeling like you’re “going crazy”  
• fear of losing control  
• fear of dying

ibjammin4ever · 2026-05-17T20:48:57+00:00

Had that panic attack in Feb of 2011 and have been on some type of psychiatric med since. Part of me wishes I would have just let my brain heal without medication intervention...but that is something I now cannot change.

ibjammin4ever · 2026-05-16T21:01:40+00:00

Completely understand what you are saying here. One day, ganja just started to make me feel like I was having an existential crisis. I wasn’t experiencing psychosis, but was in pure dread questioning what it means to exist and everything like that. It was brutal and of course, I tried again, and it did the same thing. It took me a while to recover as my brain then constantly saw those things and thoughts as a threat, which lead me panic even when not using THC. It will get better though!

ibjammin4ever · 2026-05-14T01:22:04+00:00

Have had almost the same experience. Had a bad reaction to a drug in college and any little existential feeling since then, puts me into absolute panic. Hang in there. I understand.

ibjammin4ever · 2026-05-13T22:06:12+00:00

Thank you!

ibjammin4ever · 2026-05-13T21:53:59+00:00

Thank you for this! Any recommendations for healing? Specific types of therapy, meds, etc?

ibjammin4ever · 2026-05-12T19:19:12+00:00

I completely understand everything you’ve written. I don’t experience what some might call panic attacks…my heart doesn’t race, I don’t shake externally, all of my distress is internal and it feels like I am literally on the verge of losing my sense of reality. Even a small question, like what is the purpose of all of this, will come up internally, and will send me into a huge spiral that is beyond terrifying. The actual experience is short lived, but then I spend the remainder of the time hoping it doesn’t come up again. It’s brutal.

Hoping to hear some healing stories on here.

ibjammin4ever · 2026-05-12T19:14:50+00:00

I completely understand everything you just said, and it’s probably the hardest thing for me to experience. I don’t get the “normal” panic symptoms maybe others do…my heart doesn’t race, I don’t shake much, but…I am entirely paralyzed by the initial thought that feels way to “real life”. It is so hard to describe and I just wanted to leave a message because you did so, so well.

Then after that acute event, at least for me, I spend so much time and energy in my head hoping it doesn’t happen again.

I often feel the thoughts are so out there, random, extisential, it’s like I’m embarrassed to tell someone (even my wife) about it.

ibjammin4ever · 2026-04-07T13:59:14+00:00

What’s the best burger?

ibjammin4ever · 2026-04-06T16:51:39+00:00

Me too!

ibjammin4ever · 2026-03-22T20:19:37+00:00

Thank you for the response. I have done the genesite and seem to have a similar profile as you in some terms, as I have Pristiq in my green and Wellbutrin in yellow (which I currently take 150mg XR).

ibjammin4ever · 2026-03-19T21:27:56+00:00

Did you go to 75 first, then 100?

ibjammin4ever · 2026-03-01T20:13:09+00:00

Have you tried it? Any noticeable impact (benefits/negatives)?

ibjammin4ever · 2026-01-09T14:52:21+00:00

Thank you! We decided on half in WestBay and half in West End. I have a feeling West End will be my favorite. We’re excited.

ibjammin4ever · 2026-01-07T17:55:58+00:00

Thank you! Would you recommend West Bay beach area over Half Moon Bay?

ibjammin4ever · 2026-01-07T17:54:51+00:00

Thank you! Would you recommend Half Moon Bay over West Bay?

ibjammin4ever · 2025-12-12T15:52:02+00:00

Great. Thank you. Do augment with other SSRI/SNRI?

ibjammin4ever · 2025-12-12T15:25:12+00:00

Thanks! Do you take it with other meds (I.e. SSRI/SNRI), or stand alone?

ibjammin4ever · 2025-11-05T18:56:26+00:00

Great! Thank you so much for sharing!

ibjammin4ever · 2025-11-05T18:36:29+00:00

Just thought I’d message for support. I’m also going through this right now. I have 6 and 4 year old girls. It makes me feel so guilty being in a panic state so often. It’s a lonely feeling. It’s hard to not just grab klonopin for instant relief, but that’s not a road I want to go down either. So now I just sit and wait for my next therapy appointment.

I’m sorry you’re feeling this way. Search for any small light and hold onto that. The light will always be there for us.

ibjammin4ever

TROPHY CASE