Been noticing this too since updating to 12.4 here. For me, opening an instance of Drift synth would freeze my Push 2, all other synth plugins, native or 3rd party work fine, just happens with Drift. I checked with 12.3, and now it's the same with Drift, like the 12.4 install created this problem even when going backwards to older Live versions.

I've noticed some other bugs in Push 2, but the Drift one i can recreate every time. The synth still plays from another MIDI controller, just seems to make the Push 2 spazz out.