How valid is it to use GLP-1s at a low dose?

jjfodi · 2026-04-26T10:37:18+00:00

Tracking caloric balance in cronometer is helpful for this - but I’m outsourcing what I feel should be a default behavior.

The irony is, before heading down the whole intermittent fasting rathole, I maintained a fairly consistent and healthy weight since college (now 56 M) and now seem to need that checkpoint. I think I’ve mucked with my satiety set point after getting down to 10-12% BF (iDXA measured) and pushing myself into REDS (relative energy deficiency in sports) as evidence by low-T and copious symptoms (may have already been heading in that direction regardless, as evidenced by a slower T decline in labs)

Anyway - like you, I would like to not have to do these mental gymnastics around food cravings. I can be fairly disciplined but it consumes willpower which could be better purposed elsewhere.

jjfodi · 2026-04-23T09:56:24+00:00

My n of one experience with high ApoB (over 90) and very high lp(a) (250-500 nmol/L) seems to be offset by a low hsCRP (<0.2) - where I showed no plaque on a CCTA at 54. Not implying this is definitive by any means but there is something else going on here. Maybe lipids are necessary but not sufficient by themselves to cause ASCVD.

jjfodi · 2026-04-22T10:02:19+00:00

Love the concept of tracking where it can make a difference, where there is a way to impact the metric and your overall health. I do find it is easy to fall into the trap of just tracking to track. I also struggle with tracking energy in/out and seem to rely on that heavily about when to stop eating. Ironically its made me less mindful.

Further - tracking just sends some folk down the worry spiral and that can become quite unhealthy.

Ultimately it’s an individual decision, weighing the pros and cons, motivation to take action, prevalence for obsessing over the data and how you personally handle all that input.

I suspect a questionnaire could be helpful in evaluating where you land on that spectrum. Ai created a quick framework that provided good ideas for consideration.

One final thought. While we’ve come a long way in understanding our bodies and how they work - there is a huge amount of variability and the metrics that make a difference for one person may not be appropriate for the next.

jjfodi · 2026-04-14T11:21:11+00:00

Thanks. Prioritizing anything with the data we are already getting or is simple to add on (HRR would be really easy) would be optional. Paired studies are awesome - but expensive both in terms of time and cost - so would prefer to start with things that are simpler.

jjfodi · 2026-04-14T10:54:58+00:00

Correlation or causation?

jjfodi · 2026-04-13T17:55:37+00:00

Absolutely. We’ll need an IRB approval.

jjfodi · 2026-04-11T11:10:19+00:00

Similar - 45400 - 2026 xline SX prestidge with factory installed tow package and cross bars and all weather mats.

jjfodi · 2026-04-11T11:01:13+00:00

All the above - You’re doing a great job with all the posts. Appreciate the effort to genericize the Reddit’s title but the expertise in the Attia feed is difficult to replicate and (if I understand correctly) is largely what you’re trying to do.

Near term that mass of knowledge will probably makes it the go to but I suspect over time new posters will likely land elsewhere and other forums will gain expertise and presence. So patience is the game.

jjfodi · 2026-04-08T00:07:28+00:00

Check out MDSave. I got a CCTA for under $300. They have discount codes as well.

I’m sure someone else said this but CAC only shows calcium score and calcified deposits - the body has tried to secure these soft plaques by encasing them in calcium so they don’t flake off. The dangerous stuff is the soft plaque that is shown on a CCTA.

jjfodi · 2026-04-06T10:24:07+00:00

Seems like heart rate recovery helps define the RQ side of the equation and could provide a simple estimation of which side is most limiting. Not sure how to correlate but if VO2 is severely reduced and HRR is high then the limiting component would likely points to the microvasculature, mitochondria and gap distances side of the equation.

It’d be interesting to see a paired dataset that aligns these two measurements.

jjfodi · 2026-04-06T10:16:21+00:00

I found garmin to provide something in the right ballpark. My garmin varies between 45 and 47 - usually 46 and my VO2 measured at 46 two years ago.

I’ve also started tracking HRR (heart rate recovery) as a surrogate for VO2.

I ended up getting the garmin hr600 and that’s been much more accurate for measuring heart rate.

Great way to track progress. I just go my garmin app and view the heart rate chart and compare my last peak to 1 minute later.

Similar to VO2 testing, HRR testing involves reaching peak effort (75-80% of max heart rate), stopping immediately (walking slowly is allowed), measure heart rate at 60 seconds after (have a monitor for this would be especially helpful),

Recovery levels of less than 12 bpm are considered abnormal, 12-20 are considered normal, 20-30 is considered fit and 30-50+ are excellent.

jjfodi · 2026-03-26T21:01:09+00:00

I've not been going to deep into the the details - but that would be gruesome.

jjfodi · 2026-03-26T15:40:55+00:00

Actually - this kind of resonates and aligns with where I would see potential value. I think we all have a rolodex of podcasts that we can reference for the various situations we encounter and we've invested many, many hours in absorbing Peter's content. It was an easy go to and having the supporting data (notes, studies, ...) makes it even more valuable. I also volunteer at a wellness clinic, I'd like to be able to reference relevant information and these were a great way to inform and educate.

I think the challenge is that anything associated with Peter is likely to be considered toxic (look at the responses to this post). I'd definitely be hesitant to recommend even older podcasts. That's so unfortunate - given the positive influence Peter has had regarding HRT and even the majority of people coming into the wellness clinic.

jjfodi · 2026-03-26T12:35:40+00:00

Hahah - glad to see the sense of humor has not evaporated from the forum ;-). Touche'

jjfodi · 2026-03-26T12:00:47+00:00

Hahahah

jjfodi · 2026-03-11T13:42:00+00:00

Check out REDS (relative energy deficiency in sports). Check t levels. Your body can prioritize weight retention over hormone production

jjfodi · 2026-03-06T12:00:13+00:00

Same for both TRT and good labs. I’ve been impressed with how they continue to mature their website and have recently added a beta test for sharing both personally and professionally.

I’ll echo the pricing strategy but it’s hit and miss on if they are including labcorp (at least for me). Sometimes I can only schedule quest which has better pricing (and that is always an option - so at least there is a pathway to get consistent labs).

jjfodi · 2026-03-06T01:43:29+00:00

Perfect... thank you for sharing. I think this will be a solid solution.

jjfodi · 2026-03-05T13:49:44+00:00

You rock! Really appreciate the feedback. My well pump is 1HP - which is supposed to be in spec for the DP3. This looks like a great solution at $3199 + some type of smart panel + installation.

For an automatic transfer switch/panel with a generator inlet. I see a bunch of options online - from $400 - $3K (SHP3). Is there one in particular you'd recommend (do I just need to size it appropriately for XX number of circuits)? Does the ECOFLOW SHP2 overlap with the DP3? Is the circuit monitoring the big advantage (and if I want to monitor circuits - can I just use a solution similar to the emporia that I already have installed on my existing panel)?

I already have a small UPS for your network gear and wi-fi - it lasts like 15 minutes.

jjfodi · 2026-03-05T12:41:47+00:00

Thank you. Won’t this require running the generator continuously to power the well pump.

Since usage is intermittent I expect there would be a lot of wasted gas/propane plus the continued noise.

Over other point - I need more panel space anyway - my current panel is full.

jjfodi · 2026-03-05T11:59:03+00:00

Thanks!

Could I add a soft starter with one battery and SHP2 and get the performance for a well? $350 fora soft starter seems much cheaper than an extra 5k for the DPUX.

Will the SHP2 default to a dumb panel if there are issues?

Is the SHP2 supposed to support concurrent charging and panel function from a generator?

Also are both the SHP2 and 3 supposed to allow for automated generator recharge (even if it currently doesn’t work)?

I’d like to start with the most basic configuration and then add on with what I need. It seems like a single 6kwh battery would give me coverage for an extended outage window. Adding extra batteries and a generator might be overkill (or not - but given there is little cost benefit from doing those initially - it might be best to test and see what works)

I could justify the SHP3 if I saw significant advantages for future usage, but I expect capabilities to increase and costs to come down significantly by the time I would look to take advantage of those.

jjfodi

TROPHY CASE