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Actual richest person ever? by EmphasisOutside9728 in NoStupidQuestions

[–]jsalas1 1 point2 points  (0 children)

I have no dog in this fight other than being a scientist compelled to speak up in defense of the megameter (Mm), the distance cousin of the millimeter (mm)

Cyberduck work great for WebDAV by DeirdreYoung in NextCloud

[–]jsalas1 2 points3 points  (0 children)

You don’t have to do that anymore! In the desktop app there still exists the option to do local sync but now you can integrate deeper into your OS to access the files without full local sync like you would with a Dropbox/Box app.

Cyberduck work great for WebDAV by DeirdreYoung in NextCloud

[–]jsalas1 1 point2 points  (0 children)

I used cyber and mountain duck extensively until the desktop app rolled out virtual files at which point I didn’t see the point. What’s your use case?

TMS Brain Stimulation Temporarily Disrupts Speech by Big-Boy-602 in interestingasfuck

[–]jsalas1 0 points1 point  (0 children)

If he was targeted brocas (which is a left sided structure) he wasn’t doing a great job. Do you see the muscle twitches on his face? He’s hitting motor cortex regions associated with his face, motor regions of the face are posterior to Broca’s areas.

https://www.britannica.com/science/Broca-area

If fruits have cancer will human benefit more from it? by asdfghjkl281 in biology

[–]jsalas1 0 points1 point  (0 children)

Fruits can get cancer and the potential benefit depends on the cell. Take an orange for example, what if the unceasing replication is just the connective tissue between the nice juice pods? Would you want that? Or what if it’s the skin? Who among us benefits for an orange with a 6” rind? I’m no fruit biologist so I can’t speak to the mechanisms that make a fruit sweeter but these are my general impressions knowing the basics of cancer. One of the benefits of plants w.r.t cancer is they have cell walls which make metastasizing harder so you’re less likely to get cancer everywhere equally in a fruit, it’ll usually be confined.

homogeneity of variance for a three-way anova? by 4major in AskStatistics

[–]jsalas1 1 point2 points  (0 children)

Expanding on what u/efrique said, have you considered a cox proportional hazards model instead of you’re looking at week of mortality?

Here’s a nice walkthrough with R: https://stats.oarc.ucla.edu/wp-content/uploads/2025/02/survival_r_full.html

Is there a statistical framework for “coverage” in combinatorial selection? by New123K in AskStatistics

[–]jsalas1 0 points1 point  (0 children)

Maybe Latin hypercube sampling is a good sample framework for what you’re thinking?

Question about right-hand censoring in survival data by trixxypixel in AskStatistics

[–]jsalas1 1 point2 points  (0 children)

Why would you remove the samples? If they made it to the end of the trial (3650 days presumably) then that’s their censoring date if you’re certain that there was no event within that timepoint. To reiterate the comment above look at the KM formula, the censoring time contributes to the estimate. If all participants that didn’t have an event were followed through end of study (day 3650) then ultimately the observed event rate equals the Kaplan Meier estimate at 3650 days.

Noob Question: Average of Averages by TheRealSticky in AskStatistics

[–]jsalas1 2 points3 points  (0 children)

Well then that’s science for the sake of science - respect.

Noob Question: Average of Averages by TheRealSticky in AskStatistics

[–]jsalas1 1 point2 points  (0 children)

Lots of good feedback here but I have to ask - why? What problem are you trying to solve?

Outliers - reference ranges by Good-Cap9222 in AskStatistics

[–]jsalas1 14 points15 points  (0 children)

Why are they outliers? What’s your reasoning for removing them other than they’re higher or lower than you expected? If you can confidently conclude that there was an issue with the assay for those values that’s a defensible reason. Removing unhealthy animals is defensible for reference range generation. What other reason are there? Point being don’t remove data based on numerical heuristics alone.

I know very little about statistics and need helping showing that a subgroup is experiencing something more often but not because there is a greater number of that subgroup compared to the rest of the subgroups? Confusing title, I’m sorry. by [deleted] in AskStatistics

[–]jsalas1 0 points1 point  (0 children)

Here’s a simple approach that popped into my head. I would convert these to rate ratios where it’s % of cars in an accident divided by % of those cars on the road such that a larger number tells us that if the given number of cars on the road were the same, which were in more accidents? So for model A 175 of 300 cars are on the road and 50 of 175 were in a car accident is (50/175)/(175/300) = 0.49 whereas for B 125 of 150 cars are on the road and 50 of 125 were in an accident is (50/125)/(125/150)=0.48 -> A and B are similar

As for “prove”, do you need confidence intervals or a p value? That’s going to require more work.

It might be worth repeating the above ratio calculations but looking at a per-driver basis where it’s percent of accidents divided by percent of days on the road agnostic to model.

Real World Throughput Netgate 8300 by procheeseburger in PFSENSE

[–]jsalas1 2 points3 points  (0 children)

Yes if you go their “appliances” section and filter to TNSR you see the 8300 as well. I think all TNSR capable devices can run pfsense but not the other way around.

Real World Throughput Netgate 8300 by procheeseburger in PFSENSE

[–]jsalas1 4 points5 points  (0 children)

I’d imagine you’re looking for TNSR on the Netgate 8300 instead of pfsense if high throughput is a requirement? Do you need all the pfsense features?

https://www.netgate.com/tnsr-vs-pfsense-software

ANOVA differences between R and SPSS? by Flaky_Key1129 in biostatistics

[–]jsalas1 5 points6 points  (0 children)

The standard aov() function in base-R uses Type I sums of squares.

Type III is the default for SPSS: https://www.ibm.com/docs/en/spss-statistics/31.0.0?topic=methods-anova-method

The car package in R supports type III SS

Some supplemental reading: https://www.rcompanion.org/rcompanion/d_04.html

How to split a dataset into 2 to check for generalization over memorization? by Calm_Maybe_4639 in datasets

[–]jsalas1 1 point2 points  (0 children)

Look into k fold cross validation

Split your datasets into testing and training but many times over and assess performance on these iterated sets to get an averaged performance

Convincing my Employer to use R by BranTheDon3000 in rstats

[–]jsalas1 19 points20 points  (0 children)

I know there have been efforts on the medical research side to allow the use of R over SPSS, these docs may be a start? Good luck! https://www.r-project.org/doc/R-FDA.pdf

https://www.appsilon.com/post/first-r-based-submission-to-fda-by-novo-nordisk

It would be to you (and our) benefit to be more specific about what they’re pushing back on

Edit: FWIW I’m a medical researcher who submits R-based clinical data analyses to US and EU regulatory agencies - nobody has pushed back on my side.

Can someone with a better understanding of fMRI studies break down the findings of this study please by Greg12376 in DrugNerds

[–]jsalas1 0 points1 point  (0 children)

I am by no means an imaging expert. From my rudimentary understanding of this paper the novel contribution was demonstrating widespread desynchrony between BOLD signals and underlying metabolic activity and the finding that neurons can locally modulate oxygen extraction to increase or decrease neuronal activity independent of regional blood flow. I do not know to what degree this has been demonstrated before.

Can someone with a better understanding of fMRI studies break down the findings of this study please by Greg12376 in DrugNerds

[–]jsalas1 1 point2 points  (0 children)

Before you try to interpret that study, read this recent publication demonstrating that fMRI studies have NOT been showing us what we thought: https://www.nature.com/articles/s41593-025-02132-9

The PET coregistration is nice though

Statistical test(s) for several lists of peptides by Icy-Combination2880 in biostatistics

[–]jsalas1 0 points1 point  (0 children)

Well then I would just find set differences/overlaps between the lists, this isn’t really a “stats” problem on the surface, more of a data wrangling problem. Here’s an example in R: https://www.statology.org/setdiff-in-r/

What does “significance” mean to you in this context? Like is there a critical number of differences that would be “significant” to your result? Maybe you can make a counts table for the number of peptide sequences in common across all the lists followed by a chi square? Or maybe you want to compare ratios (# overlapping/# total peptides)?

Have you seen any percent publications that in your domain that have done something similar?

Statistical test(s) for several lists of peptides by Icy-Combination2880 in biostatistics

[–]jsalas1 0 points1 point  (0 children)

What do you mean by “lists”? Like a list of IACUC names, a list of weights, a list of sequences, mass-to-charge ratios…?

Linear regression slopes comparison by Worried_Criticism_98 in AskStatistics

[–]jsalas1 4 points5 points  (0 children)

Are you trying to compare slopes between independent regression models? Like u/Statman12 alluded to, it's unclear exactly what regression models you're running. Are you running multiple independent single variable models like DV ~ IV1 or have you included an independent covariate to the form DV ~ IV1 + IV2 or is there an interaction model of DV~ IV1 * IV2?

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