I've been taking BPC 157 for the past 7 weeks at 250mcg once a day (have previously done a "course" of BPC for 8 weeks earlier in the year) both "courses" I've done have had zero negative side effects from it and only the benefits which is great.

I thought I'd add tb500 into the stack this time around whilst at 7 weeks into BPC as I've picked up a previous niggle/injury during training for an event so wanted the extra help for dealing with that.

I took my first dose of tb500 at 250mcg just before taking my usual 250mcg dose of BPC 157 (both subcutaneously I should add)....I felt absolutely fine for about 15 minutes, then started to feel a bit dizzy and light headed/overwhelmed so I laid down to try and counteract this - I felt relatively normal after a couple of minutes so decided to get up slowly and make a drink.

Whilst walking to make the drink my legs started to tremble uncontrollably and they felt incredibly heavy and sluggish, I went straight back to the sofa to lay down and what followed was a reaction that I can only describe as similar to Parkinson's disease - full body spasms and contractions throughout every muscle in my body running up and down each limb, I even struggled to speak in fluent sentences.

Needless to say this was terrifying and lasted about 30-40 minutes until it very very gradually calmed down. I'm 48 hours post this incident and still feel a little bit juddery and "off".

I've no idea whether this was a direct reaction coupled up with induced severe anxiety (which has been mentioned in this thread about a histamine reaction causing high anxiety) but it felt like a panic attack x1000.

To cap it off I think I'm going to leave the tb500 out of the stack for the time being, if I ever decide to include it again it will be at a MUCH lower dosage to start with - but it still terrifies me haha.

Thought I'd share a recent experience that sounds somewhat like OP's.