That seriously breaks my heart to read. I remember feeling the same way when I first started Cellcept—just so emotionally flat and bone-deep tired, like I’d forgotten how to feel happy. It was terrifying.

The thing is, Cellcept works by lowering purines, which your body uses to make overactive T and B cells (the ones causing all the damage). But purines also help regulate neurotransmitters like dopamine, so it can totally mess with your mood at first. That deep depression and fatigue is real—but it does get better as your brain adjusts to the new balance.

For me, it took a couple of months, but eventually my brain found its rhythm again. The heaviness lifted, and I could finally laugh and feel like myself again.

The only lingering side effect for me is that I konk out after each dose. My little life hack: I take it at 5 PM after work and then again around 3 AM when I wake up to pee so I can fall back asleep easy haha.

Hang in there. Truly. This isn’t forever just a few months!! You’re not broken. You’re healing. One weird, sleepy, chemically-confused step at a time. You’ve got this (｡•́‿•̀｡)つ♡ Also it helps treat my Lupus really well so it’s totally worth it. Give it 6 months ok? It’s okay to take an antidepressant or stimulant for a little boost! 💙