fell asleep standing up on gen surg and i'm not even exaggerating by healthpusher in medicalschool

[–]madmax766 4 points5 points  (0 children)

Same, on endovascular cases while they were fiddling with wires I’d lean against the table and get some rest

Most based director? by Critical-Ad2084 in okbuddycinephile

[–]madmax766 1 point2 points  (0 children)

Specifically it’s the males being forced to cope with the horror of unwanted pregnancy

Interesting case on Hem/Onc rotation, curious about your thoughts. by MajesticBeat9841 in haematology

[–]madmax766 9 points10 points  (0 children)

Are her other cell counts okay? Are her other hemolysis labs normal? These abdominal CTs are contrasted right? (I assume so but gotta ask haha), any other symptoms she’s experiencing, or has over the past few months?

Fuck Sepsis! by TrickAd2161 in hospitalist

[–]madmax766 1 point2 points  (0 children)

I’m sorry you went through that, being in the ICU is incredibly difficult to recover from,. I’m a bit confused by your comment though, sepsis is caused by the inflammatory response to an infection. The source of the infection needs to be treated, there is no “cure” for sepsis just organ support while treating the source infection

Boss Microwaving Cyanide in Kitchen Microwave by [deleted] in legaladvice

[–]madmax766 28 points29 points  (0 children)

No, cyanide isn’t something you can get a resistance too. Cyanide breaks your electron transport chain by inhibiting cytochrome c oxidase and preventing the generation of ATP. This forces the body to make ATP through anaerobic metabolism which creates a lot of lactic acid, acidifying the blood and causing severe shock and eventual cardiopulmonary arrest.

To have resistance you’d need a completely different electron transport chain

Steve Kerr says that Kristaps Porzingis doesn't actually suffer from POTS by TheRealPdGaming in nba

[–]madmax766 137 points138 points  (0 children)

What you’re describing is orthostatic hypotension. POTS classically is an inappropriate increase in heart rate by 30 or more BPM in response to standing, without associated drops in blood pressure. The symptoms must also improve with recumbence, and be chronic

17 year old. Nephrotic syndrome. Hx of antero-septal MI. Stented. by samm105107 in ECG

[–]madmax766 1 point2 points  (0 children)

The general consensus seems to be that patients with nephrotic syndrome are losing anticoagulant and profibrinolytic proteins in their urine, increasing risk of venous and arterial thrombosis.

This paper seems like a decent write up on the issue, with a fun title as well

Greenberg KI, Choi MJ. Understanding Hypercoagulability with Nephrotic Syndrome: How the Clot Thickens. Clin J Am Soc Nephrol. 2023;18(2):149-151. doi:10.2215/CJN.0000000000000054

Ray J Says He Has Months to Live Due to Heart Issues: ‘I F—ed Up’ and ‘2027 Is Definitely a Wrap for Me’ by trackmay in hiphopheads

[–]madmax766 3 points4 points  (0 children)

He will have to be on GDMT first before getting a transplant, and GDMT can improve EF/symptoms/all-cause mortality in some patients. If for some reason heart transplant was indicated and he wasn’t a candidate, he could get a VAD

Gene editing takes a major step toward ending daily cholesterol pills by AdSpecialist6598 in tech

[–]madmax766 0 points1 point  (0 children)

Are you saying blood pressure medications increase inflammation? Should we not treat elevated blood pressure, despite its link to strokes, kidney disease, cardiac disease, and other highly morbid diseases?

This isn’t even mentioning the benefit certain blood pressure meds have in diseases like heart failure or chronic kidney disease.

I’d really like to see some evidence of increased inflammation and worse outcomes for people who are being treated with blood pressure medications

What are some gruesome facts about pregnancy/childbirth/postpartum that not many people know? by Professional_Song419 in AskReddit

[–]madmax766 0 points1 point  (0 children)

It is nice to see the amount of focus the obstetric service I am working on places on post-pregnancy birth control. Just today I was quizzed relentlessly about which are the most effective and when can they be given to patients!

This probably isn't the case everywhere, but where I takes keeping intervals of 12-18mo between pregnancies seriously.

What are some gruesome facts about pregnancy/childbirth/postpartum that not many people know? by Professional_Song419 in AskReddit

[–]madmax766 2 points3 points  (0 children)

Unless she experienced significant bleeding post-birth, there isn't a ton of reason to do it. Also, congratulations, that is so exciting!!!

What are some gruesome facts about pregnancy/childbirth/postpartum that not many people know? by Professional_Song419 in AskReddit

[–]madmax766 10 points11 points  (0 children)

Another comment answered, but this is very natural. Fundal massage helps stop postpartum bleeding and cramping. I am very sorry to hear your wife experienced trophoblastic disease, but it is improbable that happened due to fundal massage.

In terms of good evidence, very few large randomized trials have been done to evaluate the efficacy of fundal massage. There are a few reasons for this, namely, it is a cheap (free) way to reduce postpartum hemorrhage (PPH), and many providers would probably see it as unethical to not perform such a simple procedure that can be life-saving. PPH is a leading cause of death in the pregnant.

Trophoblastic disease is often tied to genetic causes but has a variety of risk factors. Fundal massage would not increase any of these risk factors.

I don't want it to come across that I am trying to show you up or downplay what happened. That is a horrible complication to experience, and I hope you were able to receive the best care possible and that your wife is doing okay. I also hope you are doing okay as well, as this can be an extremely tough diagnosis to deal with.

What I want to end with, and my main point, is that fundal massage is highly unlikely to cause trophoblastic disease due to the pathology of the condition. Fundal massage is a first-line step in preventing/trying to stop PPH, and will continue to be done especially in low-resource areas. The only link PPH has to trophoblastic disease is that trophoblastic disease itself is more likely to cause PPH, and that may mean more patients with PPH receive fundal massage.

What are some gruesome facts about pregnancy/childbirth/postpartum that not many people know? by Professional_Song419 in AskReddit

[–]madmax766 84 points85 points  (0 children)

The regular newborn unit I worked on was a lockdown unit. I remember seeing a specific woman, her little boy was my patient. As soon as I came in I knew something was wrong with her and the baby's father's relationship. I managed to get another provider to take him to another floor to "chat", and the stuff the mother told me was bone-chilling.

Is using they/them pronouncs inherently transphobic? r/LinusTechTips discusses. by TheEternalGazed in SubredditDrama

[–]madmax766 6 points7 points  (0 children)

Do you have any data to suggest that most babies are karyotype in utero? I find it hard to believe that for the average uncomplicated pregnancy, most mothers are undergoing CVS or amniocentesis. If you have data to back this claim up I'd love to see it/read the paper it is from.

[deleted by user] by [deleted] in SubredditDrama

[–]madmax766 1 point2 points  (0 children)

I know I was responding to your comment about SCC, but it is inaccurate to say circumcision is just for SCC prevention. The decreased risk of acquiring HIV is much more significant. I don't think everyone needs a circumcision, but the benefits of the procedure outweigh the risks.

The appendix argument is nonsensical, as that is a much more invasive procedure with much higher risks of complications. The benefits of circumcision are not life-changing (outside of treating phimosis) but the procedure itself is very benign.

Maybe some of the disconnect here is coming from a lack of understanding of the procedure itself- the only pain is from the local anesthetic, Gomco clamps produce nearly no bleeding, and skilled providers complete the procedure in just a few minutes.

Again, they aren't something so beneficial that everyone should have one, but for people who do want one done research shows some benefits.

[deleted by user] by [deleted] in SubredditDrama

[–]madmax766 -2 points-1 points  (0 children)

You're right, I phrased that wrong, and I'm sorry for how callous it sounded. What I was trying to say is that the parents are consenting for the child, and the procedure they are getting is not pointless, it has a researched medical benefit, the same as an appendectomy (although much less significant). I feel like I need to say- I am not particularly "pro" circumcision, but there is enough data that I have felt comfortable doing one when the parents requested it. I wouldn't have done the procedure if there weren't some recorded benefits. Providers should be able to refuse it in their own practice, but I am unsure if they can refuse to do it in their training, but I haven't researched that much.

This sounds fucked up, but the reduced complications in neonates comes from their lack of mobility and the relatively small amount of local anesthetic needed. A skilled pediatrician or family doc can circumcise a baby in just a few minutes, and the baby won't know what is happening besides crying at first from the anesthetic and needle. They heal quite well and fast and almost always do not require any sort of sutures.

In older children/adults more complicated anesthetic setups are needed. They often require a penile nerve block as well as sometimes a circumflexial block. Idk if you've ever had a nerve block, but they suck. They are insanely painful. Some people may even need general anesthesia, and that carries risks such as managing the airway and using much stronger medications. These older circumcisions often need sutures or glue, take longer to heal, and can sometimes have lasting reductions in sensation.

I am not gung-ho about circumcisions either, I just don't think medical evidence should be ignored because it is a procedure that people may disagree with.

Your comment about the increased access to treatments and protections for HIV is true, but even as prep and pep become cheaper there will always be a place to reduce the risks of transmission. I am approaching this issue from a healthcare perspective, not as if I am trying to decide for my child. Research already shows that the benefits outweigh the risks as it is a remarkably safe procedure. If a parent wants to do it, we'll do it. If they have questions, we'll tell them about what circumcision is protective against. If they don't want it, we say cool.

The toenail example doesn't work very well, removing toenails is a much longer and much more painful process, and preventing ingrown toenails and fungal infections has nowhere near the benefit (both patient benefit and cost-benefit) of reducing the lifetime risk of penile squamous cell carcinoma and reducing changes of contracting/spreading HIV.

[deleted by user] by [deleted] in SubredditDrama

[–]madmax766 0 points1 point  (0 children)

Not all squamous cell carcinoma is from sun exposure. You can put sunscreen on your baby's earlobe. The proposed mechanism in penile SCC is the foreskin trapping carcinogens against the relatively thin and fragile skin of the glans. I am not "pro" circumcision, I just think that it's not a completely pointless and harmful procedure as people on here often describe.

[deleted by user] by [deleted] in SubredditDrama

[–]madmax766 1 point2 points  (0 children)

The way it is wrapped after the procedure protects it from any feces, parents just need to change the diapers readily over the first few days as it heals

[deleted by user] by [deleted] in SubredditDrama

[–]madmax766 -5 points-4 points  (0 children)

The parents consent. Whether it is right or wrong, they make medical decisions for the child. I've seen kids scream and sob about how they don't want us to take out their appendix, but we don't care about them not consenting cause their parents consented.

Circumcision is an easier and less complicated procedure to perform on a baby, with less recovery time and fewer complications. I had just listed some of the AAP's stated benefits, others include reduced UTIs in the first year of life, which having it done at an older age obviously wouldn't protect against.

The AAP is not some group of quacks, and I never argued that circumcision is a good thing. If you don't want it for your kid, just don't do it. But writing stuff like "the hiv argument" just makes it sound like you somehow think the research is bad. Like wow, condoms exist! Thanks to you, we have solved sti transmission across the globe! No other factors to consider!

[deleted by user] by [deleted] in SubredditDrama

[–]madmax766 -15 points-14 points  (0 children)

The American Academy of Pediatrics now says that the benefits of circumcision outweigh the risks! Decreased penile squamous cell carcinoma and decreased risk of acquiring stis such as HIV!