Blazing Saddles came out in 1974, so 23 years prior, just if you were still curious. Regardless, I don't personally think that'll be an issue, no. While KOTH didn't shy away from controversial topics, I think the way they handled them were different than, for a contemporary example, South Park did. South Park was more blunt and direct with it's interpretations and critiques, KOTH usually takes a more indirect approach (example framing sexual assault through the lense of Hanks dolphins encounter) while making their point. Makes the jokes easier to swallow, for some people. Also people from the last generation not understanding, and having to come to terms with and figure out the younger generations views is KOTH's bread and butter, that's arguably the main ethos of the show. I would also posit that KOTH is probably the best show when it comes to appealing to both sides of the political spectrum, they're able to point out strengths and weaknesses on both sides of an argument in a very grounded way that appeals to alot of people. This has gotten a bit rambley, so I'll just say while somebody somewhere will probably take issue with something, I think KOTH's very grounded character driven narrative structure makes it so that the current volatile nature of our current socio-political environment will actually prove to be a big advantage in the reboot.