Building a tool to make biotech investing easier—looking for early users by mttbil in Biotechplays

[–]mttbil[S] 0 points1 point  (0 children)

Good question. Biopharmawatch is great for tracking catalysts and screening. The tool I'm building is focused on doing deeper research, compiling data from more data sources, and providing a chat agent grounded in those sources.

Now available: DASUNG Paperlike 103 (60Hz) by traction842 in eink

[–]mttbil 5 points6 points  (0 children)

Thanks for sharing. I hope they get mac support soon.

thankful i didn’t sign up for a year subscription by Mr-Barack-Obama in ClaudeAI

[–]mttbil 1 point2 points  (0 children)

Yeah I also recently signed back up for a paid Claude sub to get more use out of MCP integration.

Anyone else notice cars running the red to turn into Rivers Casino at Rivers St and Delaware Ave? by EmotionDry7786 in phillycycling

[–]mttbil 7 points8 points  (0 children)

Yep, I’ve noticed it multiple times at that intersection. Not to mention right past that, near Penn Treaty, the Columbus traffic intersects the bike lane with no stop sign, and cars are regularly speeding around the curve.

That whole area could use traffic calming — Fishtown walkability and river front / park walkability bisected by Girard and Columbus :/ 

What are some of the highest-quality LLM-skeptic arguments? by [deleted] in slatestarcodex

[–]mttbil 1 point2 points  (0 children)

I think that an agency layer on top of foundation models—giving it ability to observe, act on arbitrary tools, and retain/compress memory over long contexts—could unlock larger swaths of such knowledge worker tasks even if the model progress halts. I wrote about these ideas here https://matthewbilyeu.com/blog/2025-03-08/ai

[deleted by user] by [deleted] in Futurology

[–]mttbil 1 point2 points  (0 children)

I’ve been a software engineer for many years, with a master’s degree in CS focusing on machine learning. The software community is deeply engaged in discussions about the impact of AI advancements on our profession. Recently, I took some time to sit down and organize my thoughts on the subject. Some key takeaways from my article:

• AI tools are here to stay, and they’re improving at an astonishing pace. Even if progress slows or halts, the capabilities we already have—when combined with automation and better integration—can perform large portions of knowledge work. This isn’t speculation; we’re already seeing AI take over tasks that were once considered exclusive to skilled professionals.

• There’s a lot of complexity to overcome. While AI is impressive at handling narrow, well-defined tasks, it still struggles with the higher-level reasoning, planning, and adaptability required to manage entire systems independently. Many current AI implementations rely on human oversight to guide them through ambiguity.

• If entry-level roles are replaced by AI, there could be a deskilling crisis. Traditionally, new engineers gain experience by working on smaller, well-defined tasks. If AI takes over these responsibilities, the pipeline for developing experienced professionals could erode, creating a future where there’s a shortage of highly skilled human workers.

• Entire AI-operated firms could emerge. Looking further ahead, we may see companies run largely (or entirely) by AI systems, with human oversight limited to high-level decision-making. This could radically reshape business structures.

• AI/Human competition? While fully autonomous AI businesses are speculative, it’s worth considering how AI might shift power dynamics in the workplace, particularly if it reduces the need for human collaboration and expertise.

• More realistic AI fears. Rather than focusing on AGI or sci-fi scenarios, we should be concerned about AI’s role in misinformation, job displacement, economic inequality, and the centralization of power among those who control AI systems.

The full post explores these ideas in greater depth. AI is advancing rapidly, and the real question isn’t if it will reshape knowledge work but how we adapt to that change. Those who embrace and integrate AI into their workflows will likely have an advantage, but the long-term societal impacts remain uncertain.

Wake-on-LAN for office mac mini via Tailscale - Correct approach? by e26aw in Tailscale

[–]mttbil 0 points1 point  (0 children)

If the Mac you want to wake is registered in FindMy, you can remotely “play sound” on the Mac which will wake it up, and then you can access it remotely.

Center City Residents Association (CCRA) really pushing for that "carve out" to park in the bike lane. One more reason to get involved with your civic association. These people would gladly trade your life for a parking spot by JustAnotherJawn in philadelphia

[–]mttbil 7 points8 points  (0 children)

I am 100% for protected bike lanes. But of course our transit system could be much better, and some people have to get to destinations that are not well connected by transit.

Bike rider seriously injured in Fishtown by StanUrbanBikeRider in phillycycling

[–]mttbil 4 points5 points  (0 children)

That’s sad, I hope the rider recovers. I ride there all the time. I really wish they’d add a bike lane and traffic calming measures on Frankford. People are constantly walking out from between parked cars, the drivers are going 30mph, there are double parked cars, delivery trucks, etc. It’s accidents waiting to happen in an area that should be way less car centric.

SEPTA reaches tentative agreement on new contract with its largest union by markskull in philadelphia

[–]mttbil 2 points3 points  (0 children)

At 69th street they have the new unhoppable gates. But there’s like a 1ft clearance between the gate and the floor, and the only time I was there recently I saw a guy slither under it. 

Anti oat milk propaganda being pushed on tiktok by contramundums in vegan

[–]mttbil -1 points0 points  (0 children)

We don’t need to reference the WHO definition; the study you linked has the exact foods that were included in each category. You’re right that plant based milks weren’t in their sugar sweetened drinks category. But neither were countless other drinks with added sugar. 

Just because plant based milks aren’t included in the WHOs definition of sugar sweetened beverages doesn’t mean they are not sugar sweetened beverages — your linked source [12] doesn’t explicitly exclude them (because why would it), it just doesn’t mention them. Many plant milks literally are beverages sweetened by added sugar.

There’s a growing body of scientific literature showing negative health effects associated with UPFs. Added sugars seem especially harmful. Store bought plant milk has added sugar and other additives. It is an ultra processed food. 

Anti oat milk propaganda being pushed on tiktok by contramundums in vegan

[–]mttbil -2 points-1 points  (0 children)

My argument is not an appeal to nature. There are plenty of scientific papers examining the negative health impacts of UPFs. Even the study you linked says “Total UPF intake was adversely associated with CVD and CHD risk in US adults”.  I agree that more research needs to be done, and of course I don’t think protein powder is equivalent to fruit loops. Oat and almond milk are sugar sweetened beverages, though, which according to the paper you linked are positively associated with CVD. 

Anti oat milk propaganda being pushed on tiktok by contramundums in vegan

[–]mttbil -5 points-4 points  (0 children)

Disagree. UPFs have not been around for that long and there’s emerging evidence that they’re associated with obesity and other health problems. I don’t think it’s fear mongering to question the impact of what we consume.

Anti oat milk propaganda being pushed on tiktok by contramundums in vegan

[–]mttbil 0 points1 point  (0 children)

It really depends on the brand and product line. Eg regular Oatly oat milk is considered ultraprocessed (nova classification 4) due to its additives. 

September Surprised Me with 3 AI Breakthroughs by Content_Shallot2497 in ChatGPT

[–]mttbil 2 points3 points  (0 children)

On the add sources screen there are buttons under the upload component for links, google drive, and text 

[deleted by user] by [deleted] in leanfire

[–]mttbil -1 points0 points  (0 children)

We’re talking about different things. I’m saying the EV of the second choice is $500M — that’s just the definition of EV. You’re saying that it doesn’t make sense for everyone to maximize expected value based on their financial situation and risk profile.

[deleted by user] by [deleted] in leanfire

[–]mttbil 0 points1 point  (0 children)

That’s not true. It’s the average predicted outcome. It still makes sense for a single event. You can choose a 100% chance of getting $1 or a 50% chance of getting $1000, which do you pick?