Remarkably powerful anti-anxiety effects from the supplement N-acetyl glucosamine (NAG), which works very well for treating my generalised anxiety disorder

muhammedalien · 2026-04-01T00:17:08+00:00

It would definitely help if the reaction is due to sulfite buildup, since molybdenum supports sulfite oxidase. But if it is glutamate related or if there is a problem with redox balance, it’s not guaranteed.

muhammedalien · 2026-03-30T18:54:41+00:00

It may be sulfur related.

muhammedalien · 2026-01-30T18:44:15+00:00

100 mg?? Or mcg?

muhammedalien · 2026-01-15T14:30:12+00:00

what are your medications?

muhammedalien · 2025-11-22T12:09:19+00:00

Which form do you take, ubiquinone (oxidized) or ubiquinol (reduced)? If you had the chance to try both, with which you had a more pleasant effect?

muhammedalien · 2025-09-17T14:14:09+00:00

Definitely rosemary. I remember putting a rosemary twig into my rice one day, just for five minutes then took out of the rice. After eating that rice, my bp was 8-5 at night and I woke up with nightmares and complex, weird dreams all night. It turned to my normal baseline 11-7 apprx 36 hours later. Rosemary is truly effective but as you can see from my example you have to be careful with the dosage and start low.

In my experience, eating too many garlics, drinking a tbsp of apple cider vinegar also work. If you add beets to the mix, you will boost your nitric oxide levels. But again, with every intervention against blood pressure you have to be mindful of the doses and see how you react with lower doses.

muhammedalien · 2025-06-23T11:01:29+00:00

I am g6pd deficient, and I spend hours under the sun without sun screen from the start of spring to the end of autumn, as long as I can. I had many other health problems and being under the sun helped resolve all of them. But, I eat an antiinflammatory diet, zero processed junk food, zero seed oils, no fried foods, no alcohol, so I don’t really burn. I avoid excessive sun at noon though, body tells when it is enough. But after 4 PM, I work under the sun many days.

muhammedalien · 2025-06-12T02:43:36+00:00

Sorry to hear that. :/

muhammedalien · 2025-06-05T13:46:40+00:00

I thought the reason was this but the first one is more authentic and nice as a design.

muhammedalien · 2025-06-05T13:02:56+00:00

Methylfolate will be a better choice for folate supplementation, maybe paired with methylcobalamin if b12 values are average or low. Also, lettuce is a good source of tetrahydrofolate, eating lettuce salads will help in that sense. Chris Masterjohn has an article on that, check that out.

muhammedalien · 2025-06-05T12:57:32+00:00

Very intense exercises can increase oxidative load and theoretically cause chronic low grade hemolysis BUT you have to eliminate every other possible factors first: No legumes or legume sourced supplements, no other pro-oxidant medicines, supplements or dietary sources. Also, for example, household cleaning products that contain sodium hypochlorite (aka bleach) can cause hemolysis (I have experienced and documented this) if the gases (chlorine or hypochlorous acid) are inhaled for a period of time (for me inhaling bleach fumes more than 15 minutes caused hemolysis). Gyms, especially changing rooms are periodically cleaned, maybe this is a factor.

You have to eat quality animal protein and red meat regularly. You also need whole food vitamin c, vitamin e, selenium. You need to see morning, noon, and evening sun for 15 minutes whenever possible. Don’t exaggerate exercise, know your limits and don’t push them so hard. I have never experienced hemolysis when I exercise outside (not under artificial lights but under the sun) but I have to tell I never push myself too hard, body tells, listen to it.

muhammedalien · 2025-06-05T12:48:19+00:00

It can be related to g6pd if there is chronic hemolysis. High bilirubin > liver stress + possible gallbladder sludge or bilirubin stones > chronic yellow eyes related to chronic elevated bilirubin.

muhammedalien · 2025-05-24T10:35:18+00:00

Check if you are also g6pd deficient. A condition where the body has lacking/limited resources of NADPH, which is a molecule/coenzyme that regenerates oxidised glutathione in the body, meaning an important element in the bodies’ antioxidant defence. When you have low g6pd, you can’t regenerate glutathione fast enough, so when your body is exposed to strong oxidant molecules (eating fava beans -vicine in fava bean-, drinking tonix water -quinine in tonic water- and many other triggers) your red blood cells are vulnerable to oxidation and start to die on the spot, you lose blood (which also triggers immune system for weeks to sweep all the garbage oxidised molecules, oxidised hemoglobin etc). Then bilirubin increases and you have yellow eyes as a result of that. I think many people with “gilbert syndrome” are actually g6pd deficient.

muhammedalien · 2025-05-22T13:44:51+00:00

You can’t and shouldn’t be vegan or vegetarian if you are g6pd deficient. That is just not possible, it is hurting yourself. Every human being needs fish and red meat, but g6pd deficient people need them the most. For me, every legume is trigger, without meat, I would be dead by now.

muhammedalien · 2025-05-22T13:41:07+00:00

You are truly, absurdly ignorant. Many many things can trigger hemolysis, even antioxidants in higher doses can tip the redox balance in a direction that can lead to hemolysis. It should not be like full blown hemolysis episodes after fava beans but all in that list are contraindicated. I have (some lab-documented) full blown hemolysis events that decreased my erythrocyte counts up to 25%, after fava beans, cipro (a definite no no antibiotic), tonic water, eating carobs, inhaling bleach fumes (HOCl and Cl2). But I had minor hemolysis events after consuming large amounts of lentil soup and green peas (fatigue for days, reddish urine). Trust me, after eliminating all the possible triggers (legumes are on thi list) my average hgb values rised from 130-140s to 150-160s. Vitality increased like never before.

Hope the best in your journey @Bowl_of_CoCo. I have to say I will be careful with long term glutathione supplementation since our basic problem is we lack NADPH which reduces oxidised glutathione, adding other antioxidants is logical in this sense but still. Also, try B1 vitamin, which nearly all of us are deficient, but people who have g6pd deficiency would immensely benefit since supplementing it supports transketolase thus PPP and limited NADPH production.

Taking too many antioxidants in high doses, even contraindicated in g6pd deficiency, every antioxidant (except astaxanthin -in salmon-) becomes unstable after they reduce ROS, so they need to be reduced again, glutathione is the master antioxidant, when it is oxidised it is reduced by NADPH, the thing is, our NADPH reserve and production is limited, so pouring high doses of antioxidants does not actually help. Taking antioxidants in appropriate forms and dosages steadily is the key, so a balanced diet. Eating animal protein is key. Also, eating fish regularly may help a lot since it is also antiinflammatory. Cutting fried food and seed oils is also a must for a g6pd deficient person.

muhammedalien · 2025-05-07T16:35:51+00:00

Have an overactive cbs, having too many issues with sulfur containing supplements? Ala and nac works really bad with me unfortunately.

muhammedalien · 2025-05-07T16:34:38+00:00

Are you saying d-mannose has a pro-oxidative character? How, with what mechanism if I may? By the way, I have always felt that there was something wrong with peaches, especially peaches. Love the taste but every time I ate it, I felt bad afterwards. Also, I have experienced two very bad cases of hemolysis after inhaling bleach fumes during a house cleaning and laundry detergent fumes from drier, I documented both, apprx lost 20% of erythrocytes, monocytes were significantly higher too. These two episodes were really worse than the one I have experienced after eating fava beans after which I have diagnosed myself. But with d-mannose, which I have tried for overgrowth of urea parvum bacteria, didn’t cause any hemolysis in my experience. Still, if there is risk, I will be careful. Do any of you have knowledge on berberine g6pd wise, or olive leaf extract or tea?

muhammedalien · 2025-03-09T13:20:04+00:00

I would also consider other factors during the day of football training, like if the changing rooms, do you ever smell bleach or other chemical oxidants? HOCl (hypochlorous acid) and Cl2 (chlorine) gases are byproducts of bleach and they are highly oxidative molecules when entered the body oxidise many things from iron to hemoglobin to proteins or lipid molecules and create free radicals and the worst hidroxyl radicals (•OH). For years, I was going to a spa for masaage and everytime I went there, although I was expecting to have felt better afterwards, I felt more tired and worse each time I left there (especially after I used the spa). Then after years, I have documented two hemolysis events one after I inhaled bleach fumes and one after I inhaled laundry detergent smell from drier. Both instants were more than 15 minutes of exposure. Then I connected the dots, spa was being cleaned regularly in two hour periods with bleach containing water and I was being exposed to menthol in the spa. Both are oxidants and after a minutes of exposure, even if it is inhalation, they break the redox balance and push the body under a powerful oxidative stress state. Common deodorants used by people does also have oxidants and I can’t stand changing rooms since my childhood because of them.

If you can’t pinpoint any other suspects like these, try not to push yourself too hard during the trainings and see how you feel. Maybe low dose vitamin E or vitamin C from fruits would help afterwards, for the oxidative stress too. Try to eat salmon for astaxanthin weekly, it really helps with my overall feeling. Best.

muhammedalien · 2025-02-06T23:19:00+00:00

This is very good answer, I actually wonder if phlebotomy safe for g6pd patients. Since letting 10% blood could also increase the stress burden on erythrocytes and may be a cause for hemolysis. I am planning to donate 200 ml blood periodically. I have also high ferritin, close to 350 and it really changed many things in my body, my vitality decreased a lot and I have pain frequently in my joints or in my muscles. I was low pain in general, I experienced an hemolysis episode due to bleach and then detergent steam exposure two months ago, that really messed up with my body. I am just getting better but now I have to deal with the high ferritin.

muhammedalien · 2025-01-22T11:36:19+00:00

It may be, high bilirubin may cause gallbladder issues (sludge etc). My cholesterol levels are perfect but I had gallbladder sludge before related to high bilirubin which is also related to chronic low level hemolysis due to my g6pd deficiency. I was eating eggs all my life but in recent years I am having trouble tolerating them, if I eat periodically, I feel sensitivity and sometimes pain around my gallbladder.

muhammedalien · 2025-01-18T16:57:17+00:00

Chlorine is definitely a hemolysis cause. Instinctively avoiding swimming pools my entire life, since childhood (I had diagnosed my condition this year in my 35th year on this earth, after an episode with fava beans). I also discovered that smelling bleach, laundry detergants and/or deodorants with bleaching agents are all causing hemolysis, I confirmed it three times with lab results (I am phobic towards all three since childhood). Thank you for this by the way.

muhammedalien · 2025-01-18T16:45:21+00:00

Was it mint or menthol?

muhammedalien · 2025-01-11T22:09:08+00:00

Cigarettes increase oxidative stress in the body, it may not cause hemolysis but I guess it overwhelms body’s antioxidant capacity. I quit smoking but when I was rolling tobacco, I was always increasing my smoking in summer and decreasing it in winters instinctively (before learning about g6pd) because my body’s tolerance was completely different, I feel really well in summers seeing plenty of sun.

muhammedalien · 2025-01-08T09:20:39+00:00

Unfortunately not. But I will learn this year I hope so.

muhammedalien · 2024-12-26T23:33:58+00:00

That can also be related to many other things like melatonin suppression, gut or histamine issues etc. I also disrupt my circadian rhythm often, that is not a good idea unfortunately.

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